The invention discloses an output feedback trajectory tracking control method with predetermined performance and dead zone input constraints for an electromechanical system. The method comprises the following steps: firstly, establishing an electromechanical system model containing dead zone input, carrying out linear processing on a dead zone model, and giving a reference tracking trajectory; secondly, defining a tracking error, introducing a predetermined performance function, and converting an original system into a system with predetermined performance constraints; in order to solve the problem that the angular position, the angular speed and the motor current in the electromechanical system are not easy to measure or the measurement precision is not high, designing a neural network state observer to estimate the state of the electromechanical system; and finally, solving the problem of complexity explosion in the traditional backstepping method by adopting a command filter technology, and constructing adaptive output feedback control in combination with an adaptive backstepping method and a neural network state observer under predetermined performance control and dead zone input constraints. The method effectively improves the transient and steady-state performance of a system with an unknown state, accurately realizes trajectory tracking, and is suitable for electromechanical system control with accurate positioning.