The invention relates to the technical field of glass processing, in particular to glass cutting and edge sealing equipment for building decoration and a use method. The glass cutting and edge sealing equipment comprises a base table, a supporting table, a supporting frame, a cutting assembly, a first moving assembly, a second moving assembly and an edge sealing assembly, wherein top blocks are driven to extrude a piece of glass by using a fifth hydraulic cylinder, fixing of glass needing to be processed is achieved, the processed glass can be stabler in a cutting process, and therefore the cutting accuracy of the device is improved, meanwhile, the accident that the glass is broken due to the fact that the glass is not firmly fixed in the glass cutting process is avoided, the using safety of the equipment is improved, plastic pads are arranged at the tops of the top blocks, a buffering effect is achieved, the top blocks are prevented from bumping the glass, meanwhile, the plastic pads also has an anti-skid effect, the fixing effect on the glass can be further improved, and therefore the cutting accuracy and safety of the equipment are further improved.