76results about How to "Maximization of overall density" patented technology

The present invention describes methods and cassettes for cell-based toxin detection and organ localization. The cassettes includes an array containing cells and a matrix of openings or depressions, wherein each region of the substrate enclosed by the opening or depression in the matrix forms a domain individually addressable by microfluidic channels in the device.

Methods for the maximizing parameter of the in vitro growth and expansion of mammalian cells, specifically postpartum-derived cells in containers such as roller bottles is described. Methods of optimizing growth rate and cell yield in such culture systems are provided. The methods are particularly adapted for human postpartum-derived cells, such as umbilicus-derived cells.

This disclosure relates to systems and methods for providing an application services cloud based on text-based messaging that hosts a plurality of application services that enables applications to be designed and delivered in a simple, productive, and extensible user experience. The present disclosure transforms any device equipped with text-based messaging into a cloud computer, a thin client with connected access to cloud-hosted applications. The disclosure overcomes heretofore unsolved platform design and implementation challenges for text-based messaging applications such as issues of user interface constraints, security, service discovery, information filtering and tracking, platform integration and extensibility, and architectural scalability.

A computer is provided having a main board with I / O connectors mounted thereon, and a chassis including a front panel providing access to the I / O connectors and to all components requiring intermittent access provided for the computer.

An axial field motor / generator having a rotor that includes at least three annular discs magnetized to provide multiple sector-shaped poles. Each sector has a polarity opposite that of an adjacent sector, and each sector is polarized through the thickness of the disc. The poles of each magnet are aligned with opposite poles of each adjacent magnet. Metal members adjacent the outermost two magnets contain the flux. The motor / generator also has a stator that includes a stator assembly between each two adjacent magnets. Each stator assembly includes one or more conductors or windings. Although the conductors may be formed of wire having a round, uniform cross-section, they may alternatively be formed of conductors having a tapered cross-section that corresponds to the taper of the sectors in order to maximize the density of the conductor in the gap between axially adjacent poles. The conductors may also alternatively be formed of traces in a printed circuit, which may have one or more layers. Each stator assembly may be removably connectable to another stator assembly to provide modularity in manufacturing and to facilitate selection of the voltage at which the motor / generator is to operate. Electrical contacts, such as pins extending from the casing, may removably connect the conductors of adjacent stator assemblies. A magnet may be dynamically balanced on the shaft by hardening a thin ring of cross-linked resin between the magnet and the shaft while the shaft is spun, using ultraviolet light to polymerize the resin.

An electrical machine having a magnet assembly with a magnet carrier ring with an even number of permanent magnets mounted in the carrier ring around a circular locus, and a conductor assembly with one or more conductor circuits wound in a double helix wave winding around a flat conductor support ring with the conductor circuits having uniformly curved conductor segments of involute or arcuate configuration wherein the magnet assembly and conductor assembly are contained in a housing with the magnet assembly rotating relative to the conductor assembly.

Methods and cassettes for cell-based toxin detection and organ localization are disclosed. The cassettes includes an array containing cells and a matrix of openings or depressions, wherein each region of the substrate enclosed by the opening or depression in the matrix forms a domain individually addressable by microfluidic channels in the device.

A method is disclosed for creating a 2D barcode. In an embodiment, the method includes: embedding primary information that can be read by a 2D-barcode-reader in a primary information pattern, and embedding secondary information that is made difficult to reproduce without alteration in a visible pattern. In an embodiment, the visible pattern is embedded within the barcode in at least one area that does not contain any primary information

The present invention generally relates to systems and methods for delivering and / or receiving a substance or substances such as blood, from subjects, e.g., from the skin and / or from beneath the skin. In one aspect, the present invention is generally directed to devices and methods for receiving or extracting blood from a subject, e.g., from the skin and / or from beneath the skin, using devices containing a fluid transporter (for example, one or more microneedles), and a storage chamber having an internal pressure less than atmospheric pressure prior to receiving blood. In some cases, the device may be self-contained, and in certain instances, the device can be applied to the skin, and activated to receive blood from the subject. The device, or a portion thereof, may then be processed to determine the blood and / or an analyte within the blood, alone or with an external apparatus. For example, blood may be received from the device, and / or the device may contain sensors or agents able to determine the blood and / or an analyte suspected of being contained in the blood. In another aspect, the present invention is generally directed to arrangements of skin insertion objects such as microneedles and methods of forming and arranging skin insertion objects. Other aspects of the present invention are directed at other devices for receiving blood (or other bodily fluids, e.g., interstitial fluid), kits involving such devices, methods of making such devices, methods of using such devices, and the like.

An electrical machine having a magnet assembly with a magnet carrier ring with an even number of permanent magnets mounted in the carrier ring around a circular locus, and a conductor assembly with one or more conductor circuits wound in a double helix wave winding around a flat conductor support ring with the conductor circuits having uniformly curved conductor segments of involute or arcuate configuration wherein the magnet assembly and conductor assembly are contained in a housing with the magnet assembly rotating relative to the conductor assembly.

A method of formatting digital data and a method of decoding the formatted digital data. User selectable format parameters vary the dimensions and other attributes of spots and the cells containing those spots as well as other features which the formatting process formats into a pattern. A method of encoding the formatted digital data using these format parameters allows for encoding a substrate optimally for any given printer or scanner. One embodiment provides for markers to facilitate determination of cell locations. In one embodiment the decoding process achieves a pyramid gain of knowledge by locating a landmark (801), which is located in a known position relative to a metasector (802), which contains information about the encoding process used to encode the main body of data (803), which the decoding process decodes to recover the original digital data. Further embodiments include encryption, transmission by facsimile, inclusion of human readable information, and automatic launches of computer files.

An axial field motor / generator having a rotor that includes at least three annular discs magnetized to provide multiple sector-shaped poles. Each sector has a polarity opposite that of an adjacent sector, and each sector is polarized through the thickness of the disc. The poles of each magnet are aligned with opposite poles of each adjacent magnet. Metal members adjacent the outermost two magnets contain the flux. The motor / generator also has a stator that includes a stator assembly between each two adjacent magnets. Each stator assembly includes one or more conductors or windings. Although the conductors may be formed of wire having a round, uniform cross-section, they may alternatively be formed of conductors having a tapered cross-section that corresponds to the taper of the sectors in order to maximize the density of the conductor in the gap between axially adjacent poles. The conductors may also alternatively be formed of traces in a printed circuit, which may have one or more layers. Each stator assembly may be removably connectable to another stator assembly to provide modularity in manufacturing and to facilitate selection of the voltage at which the motor / generator is to operate. Electrical contacts, such as pins extending from the casing, may removably connect the conductors of adjacent stator assemblies. A magnet may be dynamically balanced on the shaft by hardening a thin ring-of cross-linked resin between the magnet and the shaft while the shaft is spun, using ultraviolet light to polymerize the resin.

A method of identifying a subset of components of a system based on data obtained from the system using at least one training sample from the system, the method comprising the steps of: obtaining a linear combination of components of the system and weightings of the linear combination of components, the weightings having values based on data obtained from the at least one training sample, the at least one training sample having a known feature; obtaining a model of a probability distribution of the known feature, wherein the model is conditional on the linear combination of components; obtaining a prior distribution for the weighting of the linear combination of the components, the prior distribution comprising a hyperprior having a high probability density close to zero, the hyperprior being such that it is not a Jeffreys hyperprior, combining the prior distribution and the model to generate a posterior distribution; and identifying the subset of components based on a set of the weightings that maximise the posterior distribution.

This invention relates to a method for producing components with internal architectures, and more particularly, this invention relates to a method for producing structures with microchannels via the use of diffusion bonding of stacked laminates. Specifically, the method involves weakly bonding a stack of laminates forming internal voids and channels with a first generally low uniaxial pressure and first temperature such that bonding at least between the asperites of opposing laminates occurs and pores are isolated in interfacial contact areas, followed by a second generally higher isostatic pressure and second temperature for final bonding. The method thereby allows fabrication of micro-channel devices such as heat exchangers, recuperators, heat-pumps, chemical separators, chemical reactors, fuel processing units, and combustors without limitation on the fin aspect ratio.

Apparatus and methods for delivery of air-borne materials from pulsatile delivery devices by passing the emissions from such devices and air in a coaxial manner through a suitable mixing chamber. Preferred apparatus include a chamber defining an axis of air flow, a plurality of pulsatile delivery devices, an actuator in communication with the devices for selective actuation thereof, and a device for introducing air at a first end of the chamber and for flowing that air substantially along the axis. The pulsatile delivery devices are positioned at the first end of the chamber such that actuation of the devices emits an air-borne substance substantially along the axis of air flow.

This relates to the manner in which computers are configured in a given area in order to conserve space and to deal with cooling issues associated with the close housing of a large number of computers. Efficient arrangements for efficiently increasing the density of computer configurations are shown, particularly when used in a network server or host environment.

Method and apparatus is described for identifying a subset of components of a system, the subset being capable of predicting a feature of a test sample. The method comprises generating a linear combination of components and component weights in which values for each component are determined from data generated from a plurality of training samples, each training sample having a known feature. A model is defined for the probability distribution of a feature wherein the model is conditional on the linear combination and wherein the model is not a combination of a binomial distribution for a two class response with a probit function linking the linear combination and the expectation of the response. A prior distribution is constructed for the component weights of the linear combination comprising a hyperprior having a high probability density close to zero, and the prior distribution and the model are combined to generate a posterior distribution. A subset of components is identified having component weights that maximise the posterior distribution.

A method is disclosed for creating a 2D barcode. In an embodiment, the method includes: embedding primary information that can be read by a 2D-barcode-reader in a primary information pattern, and embedding secondary information that is made difficult to reproduce without alteration in a visible pattern. In an embodiment, the visible pattern is embedded within the barcode in at least one area that does not contain any primary information.

Medical devices and methods for delivery or implantation of prostheses within hollow body organs and vessels or other luminal anatomy are disclosed. The subject technologies may be used in the treatment of atherosclerosis in stenting procedures or be used in variety of other procedures. The systems may employ a self expanding stent restrained by one or more members released by an electrolytically erodable latch. Such release means do not connect directly to the implant, though one or more portions may contact it.

A method of subjecting a middle-distillate hydrocarbon feedstock to a hydrotreating reactions to remove heteroatoms and / or hydrogenate aromatics, and apparatus therefor. The method comprising heating a liquid middle distillates hydrocarbon feedstock to produce a heated feedstock, mixing the heated feedstock with a hydrogen-containing treating gas to produce a mixture, and bringing the mixture into contact with a hydrotreating catalyst at an elevated temperature and an elevated pressure effective for hydrotreating the feedstock. The hydrogen-containing gas is mixed with the heated feedstock in a ratio effective to fully vaporize the liquid feedstock at the elevated temperature and pressure before the feedstock is contacted with said hydrotreating catalyst. Ideally, the mixture is passed through a catalyst bed creating a pressure drop in the gas mixture equal to or less than 0.3 bar / m. Such a catalyst bed may be made of structured catalysts, such as monolithic catalysts.

This relates to the manner in which computers are configured in a given area in order to conserve space and to deal with cooling issues associated with the close housing of a large number of computers. Efficient arrangements for efficiently increasing the density of computer configurations are shown, particularly when used in a network server or host environment.

Disclosed is a sensor device (10) comprising a substrate (100) carrying a sensing element (110), and a metallization stack on said substrate for providing interconnections to said sensing element, the metallization stack comprising a plurality of patterned metal layers (130a-d) separated by insulating layers (120a-d), wherein a first metal layer (130c) comprises an electrode portion (16) conductively connected to the sensing element, and a further metal layer (130d) facing the first metal layer comprises a reference electrode portion (18), the electrode portion and the reference electrode portion being separated by a fluid channel (14) accessible from the top of the metallization stack. A method of manufacturing such a sensor device is also disclosed.

A display device for presenting product in a hanging orientation includes a plurality of hanging locations spaced apart from each other both laterally and longitudinally. The longitudinal spacing of the hanging locations provides for a layered display of product, while the lateral spacing of the hanging locations provides for the arrangement of products of varying sizes. In some embodiments, the hanging locations are also spaced apart from each other vertically. The vertical spacing of the hanging locations provides for a cascading display of product. The display device is designed to be coupled to and supported by a display fixture.

The present invention generally relates to systems and methods for delivering and / or receiving a substance or substances such as blood, from subjects, e.g., from the skin and / or from beneath the skin. In one aspect, the present invention is generally directed to devices and methods for receiving or extracting blood from a subject, e.g., from the skin and / or from beneath the skin, using devices containing a fluid transporter (for example, one or more microneedles), and a storage chamber having an internal pressure less than atmospheric pressure prior to receiving blood. In some cases, the device may be self-contained, and in certain instances, the device can be applied to the skin, and activated to receive blood from the subject. The device, or a portion thereof, may then be processed to determine the blood and / or an analyte within the blood, alone or with an external apparatus. For example, blood may be received from the device, and / or the device may contain sensors or agents able to determine the blood and / or an analyte suspected of being contained in the blood. In another aspect, the present invention is generally directed to arrangements of skin insertion objects such as microneedles and methods of forming and arranging skin insertion objects. Other aspects of the present invention are directed at other devices for receiving blood (or other bodily fluids, e.g., interstitial fluid), kits involving such devices, methods of making such devices, methods of using such devices, and the like.

Detectors determine the presence of valid sinusoids for DTMF, MF-R1 and MF-R2 protocols for encoding dialed digits. The detectors split electrical signals into subbands. Energies within the subbands are analyzed to determine a presence of sinusoids corresponding to frequencies of dialed digits. In one embodiment, the detectors comprise a PS-IIR filter to split the electrical signal into the subbands. The detectors further comprise at least one bank of filters, such as notch filters, corresponding to the number of possible relevant frequencies within the respective subbands. The detectors further comprise detection logic comprising tests, which may include analyzing the output(s) from the bank of filters. Optionally, a preclassifier is employed to predetermine which filters in the banks of filters are to be executed. The detectors, typically deployed in digital signal processors, allow for an increase in the density of detectors and provide robust performance in talk-off situations.