The invention discloses parcel sorting AGV equipment with an anti-collision structure. The parcel sorting AGV equipment comprises a horizontally-arranged bottom plate, the upper surface of the bottom plate is fixedly connected with an AGV control box, the AGV control box is cylindrical, the bottom surface of the bottom plate is provided with a guide device, the bottom surface of the bottom plate is rotationally connected with a plurality of first universal wheels, a plurality of anti-collision plates are vertically arranged at the outer side of the AGV control box, the bottom ends of the anti-collision plates are fixedly connected with the upper surface of the bottom plate, buffer plates are vertically arranged at the outer sides of the anti-collision plates, a plurality of grooves are formed in the surfaces of the outer sides of the multiple anti-collision plates, and sliding blocks are slidably connected into the multiple grooves. According to the parcel sorting AGV equipment, internal components and objects are protected by arranging the anti-collision plates, and the buffer plates are additionally arranged outside the anti-collision plates, so that the acting force generated by collision is reduced, and the buffer protection effect is achieved; and meanwhile, telescopic second universal wheels are additionally arranged, so that the stability of the equipment is improved, rollover is prevented, and the parcel sorting AGV equipment is simple and practical.