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The present invention provides methods of suppression of tumor cell proliferation and tumor growth using placental stem cells and placental stem cell populations. The invention also provides methods of producing and selecting placental cells and cell populations on the basis of tumor suppression, and compositions comprising such cells and cell populations.

One aspect of the invention is a removable strap for a snowboard boot to preventing the rider's foot from lifting in the boot. The ankle strap enables a soft boot to be used with both a strap-less step-in binding system, and a strap binding system. Another aspect is a snowboard binding including a strap adapted to releasably secure the snowboard boot and constructed and arranged to avoid creation of a pressure point at an instep bone of the rider. A further aspect is an apparatus comprising a snowboard boot and a strap attached thereto. The strap is arranged to prevent the rider's heel from lifting in the snowboard boot, and is constructed and arranged to avoid creation of a pressure point at an instep bone of the rider.

Provided are methods for ameliorating a symptom of a neuropsychiatric disorder in a subject. Also provided are methods for ameliorating at least one physical symptom or at least one psychological symptom resulting from tobacco cessation in a subject, methods for ameliorating a symptom of Alzheimer's disease or other cognitive disorder in a subject, methods for ameliorating a symptom of schizophrenia, schizoaffective disorder, or other psychotic disorder in a subject, methods for ameliorating a symptom of a depressive disorder in a subject, methods for ameliorating a symptom of bipolar disorder in a subject, methods for ameliorating a symptom of post-traumatic stress disorder or other anxiety disorder in a subject, methods for predicting a predisposition to suicide, suicidal ideation, suicidal behavior, or a combination thereof in a subject, methods for ameliorating a symptom of a pain disorder in a subject, methods for ameliorating a neurodegenerative disorder in a subject, methods for ameliorating a symptom of traumatic brain injury in a subject, methods for ameliorating a sleep disorder in a subject, and methods for improving cognitive functioning in a subject. In some embodiments, the methods include administering to a subject in need thereof an effective amount of a neuroactive steroid composition comprising pregnenolone (PG), allopregnanolone (ALLO), dehydroepiandrosterone (DHEA), progesterone (PROG), precursors thereof, metabolites thereof, pharmaceutically acceptable salts thereof, derivatives thereof, or combinations thereof.

An improved solvent system for the formulation and application of N-alkyl thiophosphoric triamide urease inhibitors. These formulations provide safety and performance benefits relative to existing alternatives and enable storage, transport and subsequent coating or blending with urea based or organic based fertilizers. These formulations are comprised primarily of environmentally friendly aprotic and protic solvents (particularly dimethyl sulfoxide and alcohols / polyols) to stabilize the urease inhibitor.

The present invention provides methods of suppression of tumor cell proliferation and tumor growth using placental stem cells and placental stem cell populations. The invention also provides methods of producing and selecting placental cells and cell populations on the basis of tumor suppression, and compositions comprising such cells and cell populations.

A method for expressing a psychological change of a character according to a positional relation, in a ball game realized by a game apparatus. The method for moving a predetermined character according to an inputted operation, executing a ball game in which a plurality of characters including the predetermined character appear, and generating an image of a virtual space in which the plurality of characters are provided, on the basis of a view point, has: determining whether a positional relation between a ball possessing character which possesses a ball and a second character, of the plurality of characters, satisfies a positional condition, or not; and changing a movement ability of at least one of the ball possessing character and the second character, when the positional relation satisfies the positional condition.

Provided are methods for ameliorating a symptom of a neuropsychiatric disorder in a subject. Also provided are methods for ameliorating at least one physical symptom or at least one psychological symptom resulting from tobacco cessation in a subject, methods for ameliorating a symptom of Alzheimer's disease or other cognitive disorder in a subject, methods for ameliorating a symptom of schizophrenia, schizoaffective disorder, or other psychotic disorder in a subject, methods for ameliorating a symptom of a depressive disorder in a subject, methods for ameliorating a symptom of bipolar disorder in a subject, methods for ameliorating a symptom of post-traumatic stress disorder or other anxiety disorder in a subject, methods for predicting a predisposition to suicide, suicidal ideation, suicidal behavior, or a combination thereof in a subject, methods for ameliorating a symptom of a pain disorder in a subject, methods for ameliorating a neurodegenerative disorder in a subject, methods for ameliorating a symptom of traumatic brain injury in a subject, methods for ameliorating a sleep disorder in a subject, and methods for improving cognitive functioning in a subject. In some embodiments, the methods include administering to a subject in need thereof an effective amount of a neuroactive steroid composition comprising pregnenolone (PG), allopregnanolone (ALLO), dehydroepiandrosterone (DHEA), pharmaceutically acceptable salts thereof, derivatives thereof, or combinations thereof.

A device for delivering a powdered medicament by inhalation comprises an air inlet passage having low pressure-drop and low turbulence for stabilizing air flow before aerosolization, a dosing cup in the region of reduced air velocity to delay aerosolization, a high pressure drop throat to generate a high velocity flow, a rapidly expanding diverging passage to create a free jet of air with high turbulence and an outlet passage having large cross-sectional area to control the rate of dissipation of the free jet. The device is simple yet capable of consistently providing uniform and effective powder aerosolization and deagglomeration over a variety of patient inhalation profiles.

A series of beverages and / or foods, which have protecting and enhancing effects on human's joints and bones and can therefore prevent and treat osteoarthritis, is provided. The beverages and / or foods comprise one or more cartilage- and synovial fluid-enhancing active ingredients or combinations of these ingredients with bone-enhancing calcium and phosphorus additives. Active ingredients in these beverages and / or foods are taken in liquid forms. So they can be easily absorbed and utilized thoroughly by human body.

An improved solvent system for the formulation and application of N-alkyl thiophosphoric triamide urease inhibitors. These formulations provide safety and performance benefits relative to existing alternatives and enable storage, transport and subsequent coating or blending with urea based or organic based fertilizers. These formulations are comprised primarily of environmentally friendly aprotic and protic solvents (particularly dimethyl sulfoxide and alcohols / polyols) to stabilize the urease inhibitor.

Provided are methods for ameliorating a symptom of a neuropsychiatric disorder in a subject. Also provided are methods for ameliorating at least one physical symptom or at least one psychological symptom resulting from tobacco cessation in a subject, methods for ameliorating a symptom of Alzheimer's disease or other cognitive disorder in a subject, methods for ameliorating a symptom of schizophrenia, schizoaffective disorder, or other psychotic disorder in a subject, methods for ameliorating a symptom of a depressive disorder in a subject, methods for ameliorating a symptom of bipolar disorder in a subject, methods for ameliorating a symptom of post-traumatic stress disorder or other anxiety disorder in a subject, methods for predicting a predisposition to suicide, suicidal ideation, suicidal behavior, or a combination thereof in a subject, methods for ameliorating a symptom of a pain disorder in a subject, methods for ameliorating a neurodegenerative disorder in a subject, methods for ameliorating a symptom of traumatic brain injury in a subject, methods for ameliorating a sleep disorder in a subject, and methods for improving cognitive functioning in a subject. In some embodiments, the methods include administering to a subject in need thereof an effective amount of a neuroactive steroid composition comprising pregnenolone (PG), allopregnanolone (ALLO), dehydroepiandrosterone (DHEA), pharmaceutically acceptable salts thereof, derivatives thereof, or combinations thereof.

A substrate cleaning method includes: a first step in which a cleaning liquid is ejected from a nozzle N2 to a central portion of a wafer W; a second step in which a dry gas is ejected from a nozzle N3 to the central portion of the wafer W to form a dry area; a third step in which the cleaning liquid is ejected from the nozzle N2 while the nozzle N2 is moved from a central side of the wafer W to a peripheral side thereof; a fourth step in which a width of an intermediate area generated between a wet area and the dry area is acquired; and a fifth step in which, when the width of the intermediate area exceeds a predetermined threshold value, a process parameter is changed such that the width of the intermediate area becomes the threshold value or less.

A portable combination exercise mat adjustable for varying degrees of difficulty is disclosed. The exercise mat combines abdominal, aerobic, weight lifting, and resistance exercises. The exercise mat is easy to produce, compact in size, inexpensive, and readily transportable.

The invention refers to hearing devices (1) and methods of operating hearing devices (1). In one aspect, the hearing device (1) comprises a power supply unit (2) comprising a primary energy storing unit (3) and, in addition, a secondary energy storing unit (4). The power supply unit (2) is configured such that the secondary energy storing unit (4) is rechargeable by means of the primary energy storing unit (3). E.g., the primary energy storing unit (3) has a higher energy density than said secondary energy storing unit (4), and the secondary energy storing unit (4) has a lower internal resistance than said primary energy storing unit (3). This allows to provide electronic circuits (11;12;13;14) of the hearing device (1) with pulsed currents. In another aspect, the hearing device (1) comprises at least one processor (10;13;14), which is alternately operated in one of at least two operating modes. A first operating mode (A) is characterized by high processing activity and high power consumption, a second (B) by low or no processing activity and low or no power consumption. This allows to use of high-clock-frequency processors in a hearing device (1).

A loop track 12 for race horses is disposed at the center of a horse race game device 10. Twelve race horses 14 run on the track 12. A gate 18 is disposed in a paddock 20 in the track 12. The gate 18 is advanced to a start point of the track 12 from the paddock 20. Twelve satellites 12 are disposed on three sides of the track 12. A large projector 24 for displaying images of developments, ect. of a race is disposed on one of the short sides of the track 12. Speakers 25 for live broadcasting, fanfares, BGM, etc. are disposed on both sides of the large projector. The horse race game device enables a larger number of running objects to be raced at once, whereby race developments are made more amusing.

A software wrapper for interfacing to pre-existing software code is provided. The software wrapper is capable of inheriting from a first application program interface (API) and a second API. For calls to the first API, the software wrapper delegates to a pre-existing enumeration of objects. The wrapper creates a vector identifying elements of the enumeration. Iterators provided by the wrapper maintain positional cursors for calls to the second API. A comparison is made between each of the positional cursors and the vector. If a positional cursor exceeds the size of the vector, additional elements are extracted from the enumeration, placed in the vector, and returned on the second API. Otherwise, if the positional cursor is smaller than the vector size, the wrapper delegates directly to the vector. The first API can be a java-based enumeration API and the second API can be a java-based collection API.

Lithographic printing plates can be obtained by contacting infrared radiation-imaged negative-working lithographic printing plate precursors with a processing solution having a pH less than 9 and comprising a UV photoinitiator. After this processing, the lithographic printing plate is floodwise exposed with UV radiation. Providing a UV-photoinitiator in the processing solution followed by UV exposure can increase imaging sensitivity and printing plate run-length, and reduce print background.

The library contains a plurality of functions and a plurality of procedures that model hardware-components of the target processor. The plurality of functions and / or a plurality of procedures are defined and described in a high-level language, e.g. C-language. All of software development can be done in the high-level language; a common source code can be used in two types (compiler type and interpreter type) of simulators without rewriting the source code. Parts of the simulators can be communalized and development efficiency improves. The executing-cycles-number is acquired and measurable.

A quiz game content producing method enables a quiz creator to make, register, and publicize a quiz game set so that other people are able to use the quiz game set in the unit of the quiz game set which comprises one or more quiz steps and game progression material. The present invention also relates to a system and a method for providing a quiz game for a quiz participant who is connected to a quiz channel by enabling a quiz operator to use a publicized quiz game set. In addition, the present invention relates to a system and a method for providing a quiz game using a bidirectional quiz step. The present invention enables a quiz creator to: compose each quiz step by using a unique creative technique in the arrangement of quiz questions or the progression schedule of a quiz game according to selections or difficulties of the overall quiz questions; and develop quiz game content of a quiz game set unit which includes the quiz step. The creation of a quiz game set can be activated by accumulating points or providing a prize for a quiz creator and a quiz operator in a process in which the quiz creator creates the quiz game set and the quiz operator provides a quiz game for quiz participants. The present invention is able to provide a quiz solving game based on the quiz game set by enabling anyone to easily open a quiz channel and invite acquaintances as quiz participants.

An elevator includes a first elevator unit vertically movable in a hoistway, and a second elevator unit vertically movable in a hoistway. At least one of said elevator units is an elevator car. One or more belt-shaped hoisting ropes interconnects the first elevator unit and the second elevator unit. A drive wheel is provided for moving said one or more belt-shaped hoisting ropes. Each of the belt-shaped hoisting ropes passes around the drive wheel and includes consecutively a first rope section extending between the drive wheel and the first elevator unit, and a second rope section extending between the drive wheel and the second elevator unit. The elevator further includes non-driven cambered diverting wheels, each said first rope section being arranged to pass around a first cambered diverting wheel, in particular resting against a cambered circumferential surface area thereof, and each the second rope section being arranged to pass around a second cambered diverting wheel, in particular resting against a cambered circumferential surface area thereof. A rope monitoring arrangement is configured to monitor displacement of each of the first rope sections in the axial direction of the wheels away from a predefined zone, and displacement of each of the second rope sections in the axial direction of the wheels away from a predefined zone. The elevator is configured to stop the rotation of the drive wheel when one or more of the first and second rope sections is displaced in the axial direction of the wheels away from a predefined zone.

Provided are methods for ameliorating a symptom of a neuropsychiatric disorder. Also provided are methods for ameliorating at least one symptom resulting from tobacco cessation; and for ameliorating a symptom of Alzheimer's disease or other cognitive disorder; of schizophrenia, schizoaffective disorder, or other psychotic disorder; of a depressive disorder; of bipolar disorder; of post-traumatic stress disorder or other anxiety disorder; of a pain disorder; or of traumatic brain injury. Also provided are methods for ameliorating a sleep disorder; for improving cognitive functioning; for predicting a predisposition to suicide, suicidal ideation, and / or suicidal behavior; and for ameliorating a neurodegenerative disorder. In some embodiments, the methods include administering to a subject in need thereof an effective amount of a neuroactive steroid composition, pharmaceutically acceptable salts thereof, derivatives thereof, or combinations thereof.

A trailing arm bush may include a cylindrical outer pipe, an inner pipe inserted to a central portion of the outer pipe at an interval, a first bush rubber unit, a second bush rubber unit and a third bush rubber unit that connect between an inner peripheral surface of the outer pipe and an outer peripheral surface of the inner pipe, respectively, a hollow void part formed between the inner peripheral surface of the outer pipe and the outer peripheral surface of the inner pipe, and a stopper attached to the inner peripheral surface of the outer pipe and disposed among the first bush rubber unit, the second bush rubber unit and the third bush rubber unit.

A method for generating a cryptographic key, wherein a first node transmits a first signal on a first channel to a relay, a second node transmits a second signal on a second channel to the relay, the first node receives a third signal from the relay on the first channel and a fourth signal derived at least from the first signal and from the second signal, the second node receives the third signal and the fourth signal from the relay on the second channel, the first node determines the key based on the first signal, on the third signal and on the fourth signal and the second node determines the key based on the second signal, on the third signal and on the fourth signal.

The invention provides a novel game apparatus which permits a player to develop or maintain a skill, such as putting a golf ball, to achieve values used in one or more of a selection of pre-existing games of strategy and / or chance, such as card games, thereby allowing the skill development and maintenance to be more entertaining. The apparatus comprises a wall with a plurality of openings, each of which is associated with a value based on a pre-existing game which a player may obtain by propelling the ball into the opening.

The purpose of the invention was to develop a training device that allows acquiring sense of water immediately after workouts with it.The possible embodiment comprise an elastic or stretching material with gaseous medium between water and sportsman's palm and (or) forearm, and at least one valve. The embodiment allows to create the artificial gaseous medium at the inner side of human hand and / or forearm in water and to change its pressure and volume. The gaseous medium pressure and volume are set for a sportsman to change his psychosomatic sensations and lead to changes in mechanics and dynamics of the sportsman strokes in water.The invention with gaseous medium assists swimmer to improve his ability to sense water. If pressure of gaseous medium is properly selected there is an effect of vanishing support during execution of strokes. The effect occurs due to properties of fluent gaseous medium in elastic / stretchy material. Shape of the gaseous medium is very responsive to propulsive forces during underwater part of a stroke. The gaseous medium deformations by water streams / flows cause feedback to swimmer hand, arm, and brain about applied forces. Interactive perception of water through the vanishing gas support assists swimmer to find right mechanics and dynamics of strokes that correspond with the current factors influencing swimming. In other words the device assists in development of human physical qualities required for increase in efficiency of applying hand's (or arm's) force during underwater part of strokes. A sportsman recalls the developed mechanics and dynamics right after workout with the device and its doffing.

A carbonaceous material for electric double-layer capacitors that is based on a plant-derived carbon precursor, in which carbonaceous material: a BET specific surface area is 1,900 to 2,500 m2 / g; an average pore size is 2.2 to 2.6 nm as determined by a nitrogen adsorption method; a volume of micropores having a pore size of 2 nm or smaller is 0.84 to 1.30 cm3 / g as determined by the MP method; a ratio of a volume of micropores having a pore size of 1 to 2 nm with respect to the volume of the micropores having a pore size of 2 nm or smaller is 25 to 50% as determined by the MP method; and a volume of mesopores having a pore size of 2 to 50 nm is 0.16 to 0.4 cm3 / g as determined by the BJH method.

A substrate cleaning method includes: a first step in which a cleaning liquid is ejected from a nozzle N2 to a central portion of a wafer W; a second step in which a dry gas is ejected from a nozzle N3 to the central portion of the wafer W to form a dry area; a third step in which the cleaning liquid is ejected from the nozzle N2 while the nozzle N2 is moved from a central side of the wafer W to a peripheral side thereof; a fourth step in which a width of an intermediate area generated between a wet area and the dry area is acquired; and a fifth step in which, when the width of the intermediate area exceeds a predetermined threshold value, a process parameter is changed such that the width of the intermediate area becomes the threshold value or less.