The invention provides novel antibiotic
bone cement and a preparation method thereof. The material comprises a component A and a component B; the component A comprises
bisphenol A
glycidyl methacrylate,
triethylene glycol dimethacrylate, a developing agent, an
inorganic filler, an initiator and an antibiotic; the component B comprises
bisphenol A ethyoxyl dimethacrylate,
triethylene glycol dimethacrylate, a developing agent, an
inorganic filler, an accelerator and an antibiotic. The invention further relates to the preparation method of the material. According to the invention, various
bone cement products containing different
antibiotics are prepared, wherein the antibiotic with poor
thermal stability can be inactivated due to heating when being used in PMMA (
polymethyl methacrylate) bonecement so as to reduce or lose the
antibacterial property, but is still kept having the excellent
antibacterial property in the product provided by the invention, thereby expanding an antibiotic userange of the
bone cement; moreover, compared to the PMMA bone
cement containing the antibiotic in the market, the product provided by the invention is wider in antibacterial spectrum, higher in
antibacterial property and smaller in toxic or
side effect.