The invention is a multiple anti-falsification ink with a memory code and a method of detecting the ink marks of writing with it, synthesized of general ink, magnetic memory material, infrared fluorescent material and UV fluorescent material, etc. and the detecting method: making magnetic-electric conversion on the code information in the magnetic material in the ink marks and detecting, identifying the code information, and the infrared light generator excites infrared fluorescent information in the ink marks and the UV light of the UV lamp excites long-short wavelength UV fluorescent information in the ink marks. It has good anti-falsification effect, and the handwriting contains an electromagnetic code, infrared fluorescent information and UV fluorescent information, detected by special apparatuses and the code has uniqueness, so that the falsifier is difficult to simulate, thus able to effectively the occurrence of forging signatures, altering, forging written pledges, and other illegal activities. It is applied to important bills of documents and notes, signature, contracts and documents, etc.