The invention relates to a patient follow-up system for clinical medicine and scientific research, which consist of a patient management module, a follow-up list module, a short message module, an incoming call module, a medical personnel management module, a super administrator module, a follow-up question type management module, a questionnaire management module, a data import and export module, a scanning image management module, a department message management module, a senior query module, a disease classification management module, a batch print module and a statistical analysis module; and a function module is developed based on a Microsoft WINNT4.0 Server operating platform and runs on a server, is externally connected with a modulator-demodulator, contains GSM (Global System for Mobile Communication) / GPRS (General Packet Radio Service) / CDMA (Code Division Multiple Access) double-frequency communication chips and a GSM Modem for supporting EGDM900 / 1800 Mhz double-frequency communication and is simultaneously connected with a telephone set, a printer and a medical image film scanner. The patient follow-up system has the beneficial effects that patient resources and disease prognosis data are ensured to be saved; and by means of a network and communication technology, a patient is periodically visited and managed, and the results are tidied and analyzed.