The invention discloses a low-consumption digital decimation filter bank with variable decimation multiples and a digital decimation and filtering method. The low-consumption digital decimation filter bank and the digital decimation and filtering method are used for the filtering and the decimation of data. The filter bank comprises a first stage, a second stage and a third stage, wherein the first stage is a cascading comb-shaped integrating filter which is used for achieving the decimation movement with large multiples, the second stage is a half-band filter of at least one stage which is used for achieving the decimation movement of the second stage, the third stage is a compensating filter which is used for compensating pass band damping and carrying out filtering decimation movement, and the first stage is the cascading comb-shaped integrating filter with variable decimation multiples in a non-recursion mode. The method comprises the steps of determining decimation ratios and the system structure of the decimation filter bank, decomposing the transfer function of the cascading comb-shaped integrating filter, selecting the decimation ratios meeting requirements to for combination and carrying out multi-phase decomposition on the cascading comb-shaped integrating filter, the half-band filter and the compensating filter. The low-consumption digital decimation filter bank with the variable decimation multiples and the digital decimation and filtering method have the advantages that the number of registers working close to high frequency can be reduced, resource consumption is reduced, and power dissipation is reduced.