The invention discloses a main road intersection entrance lane vehicle speed control method based on cooperative vehicle infrastructure. The method comprises the steps that by means of a roadside information acquisition and processing module, whether a vehicle passes a stop line or not is calculated according to the distance between the vehicle and a main road intersection, a current running speed and acceleration, and the roadside information acquisition and processing module feeds back a calculation result to a vehicle-mounted information acquisition and processing module and conduct operating recommendation. According to the main road intersection entrance lane vehicle speed control method based on the cooperative vehicle infrastructure, by combining the vehicle-mounted information acquisition and processing module, the roadside information acquisition and processing module, an information communication module, a vehicle speed control recommendation module and a front and back vehicle safe distance warning module, information interaction between vehicles and between the vehicles and roads is achieved, the remaining time of green lights at the intersection, vehicle position, vehicle running state and weather information are integrated, and therefore the running speed of the vehicle is controlled and prompted, and safety warning is conducted on the distance between the front vehicle and the back vehicle; the traffic operation efficiency of the intersection can be improved conveniently, traffic accidents and meaningless accelerations are reduced, it is guaranteed that the vehicles run safely, oil consumption is reduced, and the environment is protected.