9 results about "Viral spread" patented technology

The utility model discloses a ceiling type air purification sterilizing device for preventing and treating infectious diseases. The ceiling type air purification sterilizing device comprises a cylindrical sterilizing box, an air guide device is arranged in the sterilizing box, a trumpet-shaped air inlet is formed in the lower end of the sterilizing box, and an exhaust port is formed in the side face of the upper end of the sterilizing box; compared with the prior art, the disinfection box has the beneficial effects that after air below the indoor disinfection box is sucked into the air inlet, the air is transversely discharged outwards from the air outlet after disinfection treatment, and the discharged air contains a disinfectant component with a certain concentration, so that viruses in public places can be effectively disinfected; meanwhile, due to the fact that the disinfecting and killing box is installed on the ceiling, air in the space below the disinfecting and killing box can be fully absorbed and treated, the exhausted air flow containing disinfectant components flows in the space from top to bottom, full-coverage and dead-corner-free disinfecting and killing are achieved, the air disinfecting and killing treatment effect is effectively improved, and a virus transmission chain is blocked.

The invention relates to the technical field of spreading modes of human viruses, in particular to a virus spreading mode prediction model based on interaction of virus protein and human protein, a prediction model construction method and a prediction method. The method specifically comprises the following steps: S1, constructing a training data set of a virus transmission mode; s2, based on the data in the S1, obtaining a virus-human protein interaction prediction result, vectorizing the prediction result by using 0 / 1 coding, and constructing a virus-human protein interaction matrix; and S3, using a machine learning algorithm and a feature selection project to construct and train a virus propagation mode prediction model based on the interaction of the virus protein and the human protein. The method for predicting the virus propagation mode of interaction between the virus protein and the human protein is convenient to use and wide in application range; the method is especially suitable for new viruses or unknown viruses which are not fully researched, and can realize efficient and rapid propagation mode identification.

In the present invention, cyclic dinucleotides or their compositions are used as biological response modifiers to enhance the immune response of subjects with deficient immune systems, with a low or absent response to vaccine antigens, or with a deficient immune response to pathogens. The formulations of the present invention are capable of modifying the biological response in such a way as to eliminate the lack of response, resulting in the development of a high-avid immune response that prevents disease caused by infectious agents, particularly viruses with the ability to evade immune surveillance mechanisms and, consequently, suppress the induction of an effective, high-avid adaptive response.The present invention also comprises cyclic dinucleotide formulations, which can be administered alone, in combination with other biological response modifiers, or in vaccine formulations with antigens. The proposed invention further includes a method for preventing or treating acute respiratory infections, preventing disease severity, and blocking transmission by inducing an immune response at the point of entry (nasopharyngeal mucosa), preventing or reducing person-to-person transmission of pathogens / viruses in preventive vaccine formulations, as well as in formulations used for prophylaxis before and after exposure to acute respiratory infections.

The present application relates to compositions and methods for: (a) preventing or treating viral infections; and / or (b) preventing the transmission and / or spread of infections. In some embodiments, the present application provides chimeric proteins comprising a target-binding moiety that specifically binds to a virus, and a positively charged mucoadhesive peptide fragment. Compositions comprising the chimeric proteins described herein are useful for preventing or treating viral infections, preventing the transmission of a viral infection from an infected individual to a non-infected individual, and for preventing the spread of a viral infection within a population of individuals.

This item is a cover for a box-shaped livestock storage rack that has multiple storage spaces capable of accommodating livestock such as chickens. It is used to prevent the spread of viruses during disease control operations in the event of an outbreak of livestock infectious diseases such as avian influenza. The right and left sides of the cover are each provided with a zipper, one near the left edge and one near the right edge, extending from the bottom edge to near the top edge. As shown in the reference perspective diagram of the usage state, when both zippers are opened, the portion sandwiched between these zippers can be rolled up to expose the livestock storage rack, allowing for work on the rack, such as storing livestock. Each edge of the top surface of the cover is provided with a flap that protrudes outward, and this flap can be grasped to attach or detach the cover.

Embodiments of the present application provide a virus infection prediction method and device, electronic equipment and storage medium. The method comprises obtaining sewage samples of a plurality of preset monitoring sites, performing gene sequencing on the sewage samples of each monitoring site to obtain gene sequence data of each monitoring site, and performing virus concentration identification on the sewage samples of each monitoring site to obtain the virus concentration of each monitoring site; performing gene analysis on the gene sequence data of each monitoring site, and constructing a phylogenetic tree corresponding to the plurality of monitoring sites based on the gene analysis result; determining a virus transmission path based on the phylogenetic tree, and updating parameters of a virus infection model based on the virus transmission path; and performing infection prediction on the virus concentration of each monitoring site based on the parameter-updated virus infection model to obtain a virus infection trend. The method can provide virus infection prediction accuracy.

The invention discloses an HIV patient intelligent administration compliance management system, which comprises an intelligent sensing layer, a data processing layer and an application service layer, and realizes data interaction through an Internet of Things (IoT) communication protocol (preferably Bluetooth 5.0, NB-IoT). The system is used for solving the problems of self-report deviation, dependence on active operation, lack of drug storage monitoring and insufficient privacy protection in HIV patient administration compliance management. Through the comprehensive action of the technical effects, the drug administration compliance rate of the HIV patient can be remarkably improved: on one hand, the conditions of missing taking, wrong taking and invalid taking of drugs are reduced through accurate monitoring and dynamic reminding; on the other hand, the problem of compliance caused by side effects, scene changes and the like can be solved in time through personalized intervention of medical staff based on real data, the risk of virus drug resistance is reduced, the long-term treatment effect of patients is finally improved, the disease deterioration and virus propagation probability is reduced, and the method has important clinical application value and public health significance.

According to some embodiments, a carrier for reducing a likelihood of a pathogen binding to cell structures of a host comprises a core, surface features extending from an exterior surface of the core, wherein the surface features are configured to bind to target areas of cell structures of the host to at least partially block the pathogen from binding to said target areas as a result of competitive inhibition, and a plurality of binding sites along the exterior surface, wherein the binding sites are configured to attract at least one portion of the pathogen, wherein the binding sites are recognizable by the pathogen and are able to be bound by the pathogen, thereby at least partially immobilizing the pathogen and reducing the likelihood of the pathogen binding to target areas of cell structures of the host.

To provide novel antiviral treatments, pharmaceutical products, and chemicals that can be used to prevent viral infection and / or viral spread in subjects exposed to, infected with, or at risk of viral infection. [Solution] An azelastine compound in an antivirally effective amount for use as an antiviral substance in a pharmaceutical formulation.