2 results about "Viral spread" patented technology

In the present invention, cyclic dinucleotides or their compositions are used as biological response modifiers to enhance the immune response of subjects with deficient immune systems, with a low or absent response to vaccine antigens, or with a deficient immune response to pathogens. The formulations of the present invention are capable of modifying the biological response in such a way as to eliminate the lack of response, resulting in the development of a high-avid immune response that prevents disease caused by infectious agents, particularly viruses with the ability to evade immune surveillance mechanisms and, consequently, suppress the induction of an effective, high-avid adaptive response.The present invention also comprises cyclic dinucleotide formulations, which can be administered alone, in combination with other biological response modifiers, or in vaccine formulations with antigens. The proposed invention further includes a method for preventing or treating acute respiratory infections, preventing disease severity, and blocking transmission by inducing an immune response at the point of entry (nasopharyngeal mucosa), preventing or reducing person-to-person transmission of pathogens / viruses in preventive vaccine formulations, as well as in formulations used for prophylaxis before and after exposure to acute respiratory infections.

Embodiments of the present application provide a virus infection prediction method and device, electronic equipment and storage medium. The method comprises obtaining sewage samples of a plurality of preset monitoring sites, performing gene sequencing on the sewage samples of each monitoring site to obtain gene sequence data of each monitoring site, and performing virus concentration identification on the sewage samples of each monitoring site to obtain the virus concentration of each monitoring site; performing gene analysis on the gene sequence data of each monitoring site, and constructing a phylogenetic tree corresponding to the plurality of monitoring sites based on the gene analysis result; determining a virus transmission path based on the phylogenetic tree, and updating parameters of a virus infection model based on the virus transmission path; and performing infection prediction on the virus concentration of each monitoring site based on the parameter-updated virus infection model to obtain a virus infection trend. The method can provide virus infection prediction accuracy.