The invention discloses sterilizing equipment with an inner wall cleaning mechanism for rice wine production and processing, the sterilizing equipment comprises an outer shell, heat preservation cotton and an inner cavity, a control panel is mounted on one side of the heat preservation cotton, a bracket is fixed at the bottom end of the outer shell, and a cleaning mechanism is arranged in the outer shell; the cleaning mechanism comprises a scraping strip, a supporting frame, a servo motor, an auxiliary frame, a transmission shaft, a push rod, a sliding rod and a telescopic spring, the servo motor is installed at the top end of the outer shell, and the bottom end of the servo motor is connected with the transmission shaft. The servo motor is started to drive the transmission shaft to rotate, meanwhile, the supporting frame rotates, the scraping strip scrapes rice wine on the inner wall of the inner cavity, the telescopic spring drives the scraping strip to move left and right, the scraping strip is tightly attached to the inner wall of the inner cavity all the time, and the sliding rod slides in the supporting frame, so that the scraping strip is enabled to keep balanced and prevent from shaking, therefore, the inner wall cleaning function of the device is achieved, the inner wall of the device can be cleaned conveniently, and the inner wall of the device is kept clean.