The invention relates to a low-temperature liquid temperature and pressure measurement lead wire device, which includes a temperature measurement lead wire sleeve, a pressure measurement communication pipe, a first sealing flange, a second sealing flange, a first sealing member, a second sealing member, a nut and a base ; A first seal and a second seal are arranged axially inside the base; the bottom end of the first seal is in the shape of an annular groove, which is used to match the protrusion on the top of the second seal; the first seal and There is a first sealing flange between the second sealing parts; a second sealing flange coaxial with the first sealing flange is arranged in the second sealing part; the temperature measurement lead sleeve and the pressure measurement connecting pipe are a set , pass through the first sealing member and the second sealing member, and be welded on the first sealing flange and the second sealing flange; the top of the base is provided with a nut, and the nut is sleeved on the periphery of the first sealing member. The device of the invention is used to monitor the low-temperature liquid environment in real time, and the measurement is relatively accurate, and the invention has simple structure, convenient assembly and good insulation and sealing performance.