A scoliosis activity suit includes a body-wrapping portion and a correction portion. The correction portion has a front segment, a rear segment, a shoulder-pulling segment, a chest-pressing segment, a pelvis-lifting segment, and a upper trapezius pressing segment. The shoulder-pulling segment, the chest-pressing segment, the pelvis-lifting segment, and the upper trapezius pressing segment are formed on a front side of the body-wrapping portion and extend to the rear segment of the correction portion. To users with scoliosis, the correction portion generates a 3D compression force on different portions of the spine of the user, such that a backward pulling force against a protracted portion of the shoulder, an uplifting force against an inclined portion of the pelvis, and a pulling force against portions with spinal sidebend can be provided. Besides, being lightweight and easy for users to wear, the suit fulfills practice of daily life adjustment and correction for scoliosis.