The application discloses a three-dimensional
image registration method, comprising the steps of: obtaining the position of a mark point on a phantom in a phantom coordinate
system; obtaining a three-dimensional image of the phantom through a C-arm
scanner, periodically obtaining the
pose of the C-arm in the scanning process, and constructing a C-arm coordinate
system; identifying the position of the mark point in the three-dimensional image, and calculating the transformation relationship between the image coordinate
system and the phantom coordinate system; calculating the transformation relationship between the C-arm coordinate system and the phantom coordinate system according to the
pose of the C-arm and the phantom identified by an
optical tracking system, and calculating the transformation relationship between the C-arm coordinate system and the image coordinate system. In the application, the use of intraoperative positioning mark points is removed, the registration accuracy is ensured, the surgical process is simplified, and the surgical efficiency is improved.