37results about How to "Maximization of detection" patented technology

One embodiment of the invention is directed to an imaging probe which comprises a first element supplying electromagnetic radiation in a forward path for illuminating a forward field of view of space in front of the probe, a second element supplying electromagnetic radiation in a sideways and / or rearward path for illuminating a sideways and / or back field of view of space alongside the probe and an image sensor. The probe further includes an imaging device in imaging paths imaging the forward and sideways and / or back fields of view onto the image sensor. Preferably the forward path, the sideways and / or rearward path and the imaging paths are unobstructed by any component of the probe. Preferably the forward and sideways and / or back fields of view are registered in a fixed spatial relationship relative to one another on the image sensor. This probe can also be used with existing endoscopes or laparoscopes so that it will be easily merged into current instruments of different manufacturers, making it easier and cheaper to use this product without the expense of a totally new endoscopy or laparoscope platform. This probe can also be used to image objects in inanimate environments as well, such as in containers, buildings, rooms, engines and pipes.

A method and apparatus of interrogating an addressable array unit, which includes a substrate, a light reflecting layer on a front side of the substrate, and a plurality of features on a front side of the array. The method may include, for each of multiple features, illuminating the feature simultaneously with reflected and non-reflected interrogating light. A light emitted from respective features is detected. Either or both, constructive interference of interrogating light at the features, or constructive interference of light emitted from the features, can be obtained to allow lowering of light power from the source, enhanced signal, or reduced noise, or combinations of the foregoing. High depth discrimination may also be obtained without the need for a confocal detection system with conventional pinhole.

An apparatus comprising a laser transmitter having a first side and a second side, a filter coupled to the first side, a detector coupled to the second side, and a temperature controller coupled to the laser transmitter and the detector. Also disclosed is an apparatus comprising at least one processor configured to implement a method comprising receiving a photocurrent of a backward light from a laser, determining a wavelength shift offset between a wavelength of the output light and a filter transmission peak, and adjusting a temperature of the laser to substantially reduce the wavelength shift and align the wavelength of the output light with the filter transmission peak.

An obstacle detector configured to identify negative obstacles in a vehicle's path responsive to steering a laser beam to scan high priority areas in the vehicle's path is provided. The high priority areas can be identified dynamically in response to the terrain, speed, and / or acceleration of the vehicle. In some examples, the high priority areas are identified based on a projected position of the vehicles tires. A scan path for the laser, scan rate, and / or a scan location can be dynamically generated to cover the high priority areas.

An improved sensor array for a mobile vehicle. More particularly, the primary objective of the present invention is to provide mobile vehicle (10) traveling in a forward direction with a sensor array (12). Sensor array (12) comprises a first sensor (16) mounted to mobile vehicle (10) at a maximum lateral distance from said vertical axis of rotation (21) near a first side of mobile vehicle (10) and a second sensor (18) mounted to mobile vehicle (10) at a maximum lateral distance from said vertical axis of rotation (21) near a second side of mobile vehicle (10). First sensor (16) and the second sensor (18) emit object detecting beams for detecting an object (39) ahead of mobile vehicle (10). A plurality of other object detecting beams are emitted obliquely to the object detecting beams of sensor (16) and sensor (18). These other beams, in conjunction with the object detecting beams from sensor (16) and sensor (18) form zones of overlapping beam coverage for better detection of objects.

Provided is a method and apparatus for segmenting airways and pulmonary lobes. An image processing apparatus obtains a first candidate region of an airway from a three-dimensional (3D) human body image by using a region growing method, obtains a second candidate region of the airway based on a directionality of a change in signal intensity of voxels belonging to a lung region segmented from the 3D human body image, segments an airway region by removing noise based on similarity of a directionality of a change in signal intensity of voxels belonging to a third candidate region acquired by combining together the first and second candidate regions. Furthermore, the image processing apparatus segments a lung region from a 3D human body image by using a region growing method, obtains a fissure candidate group between pulmonary lobes based on a directionality of a change in signal intensity of voxels belonging to the lung region, reconstructs an image of the lung region including the fissure candidate group into an image viewed from a front side of a human body and generates a virtual fissure based on a fissure candidate group shown in the reconstructed image, and segments the pulmonary lobes by using the virtual fissure.

A CMOS-implementable TOF detector promptly collects charge whose creation time can be precisely known, while rejecting collection of potentially late arriving charge whose creation time may not be precisely known. Charges created in upper regions of the detector structure are ensured to be rapidly collected, while charges created in the lower regions of the detector structure, potentially late arriving charges, are inhibiting from being collected.

A data independent acquisition method of mass spectrometry for analysing a sample as it elutes from a chromatography system is disclosed. The method comprises the steps of: ionising the sample to produce precursor ions, selecting a precursor mass range for the sample to be analysed, performing a plurality of MS1 scans and performing at most two sets of MS2 scans. Each of the MS1 scans uses a mass analyser operated at a first, relatively higher resolution, for identification and / or quantitation of the sample in the MS1 domain across the precursor mass range. The set of MS2 scans comprises performing MS2 scans of fragmented mass range segments performed with the mass analyser, operated at a second, relatively lower resolution. In the method, the MS1 scans are interleaved throughout the performing of the set of MS2 scans such that the MS1 scans provide a mass chromatogram of the sample.

Peptide antigens corresponding to amino acid residues 2-12, 1-12, 2-15 and 1-15 of parathyroid hormone (PTH), antibodies having an affinity to such peptide antigens and methods of producing the same. Such antigens, antibodies and methods producing the same according to the present invention are useful in determining bioactive intact PTH levels in serum, plasma, and / or cell culture media. Such antibodies further possess a high degree of species cross-reactivity, but substantially mitigated cross-reactivity to non-whole PTH peptide fragments and little to no recognition of the first amino acid residue of PTH.

One embodiment of the invention is directed to an imaging probe which comprises a first element supplying electromagnetic radiation in a forward path for illuminating a forward field of view of space in front of the probe, a second element supplying electromagnetic radiation in a sideways and / or rearward path for illuminating a sideways and / or back field of view of space alongside the probe and an image sensor. The probe further includes an imaging device in imaging paths imaging the forward and sideways and / or back fields of view onto the image sensor. Preferably the forward path, the sideways and / or rearward path and the imaging paths are unobstructed by any component of the probe. Preferably the forward and sideways and / or back fields of view are registered in a fixed spatial relationship relative to one another on the image sensor. This probe can also be used with existing endoscopes or laparoscopes so that it will be easily merged into current instruments of different manufacturers, making it easier and cheaper to use this product without the expense of a totally new endoscopy or laparoscope platform. This probe can also be used to image objects in inanimate environments as well, such as in containers, buildings, rooms, engines and pipes.

An endoscope comprising a first light source for illuminating biological tissue with light, a first detector for detecting macroscopic images and fluorescent images from the tissue by reflected light and fluorescent light induced in the tissue, a second light source for illuminating the tissue with light, a confocal microscopic waveguide for supplying light from the second light source to the tissue and for supplying microscopic fluorescent images of the tissue, and a second detector for detecting the microscopic fluorescent images from the confocal microscopic waveguide.

A sensor for night vision applications is provided, wherein the sensor comprises a semiconductor absorption layer of composition that limits long wavelength response cutoff to between 1.25 to 1.4 μm wavelength. The selection of this cutoff frequency provides improved dark current performance, thereby requiring less cooling of the sensor. Consequently, energy consumption is reduced, as the sensor does not require active cooling, so that the sensor is particularly beneficial for mobile night vision applications where battery weight is of high importance.

A metal detector adapted to generate a transmit search signal and to receive a receive search signal, and to analyse such received search signal, wherein the detector is adapted to allow a selection of operating parameters for each of these functions, said selection being effected by the storage as data in a memory of such selection, characterised in that the detector is adapted to allow such stored data to be modified in accordance with data in an external store, further characterised in that there is a digital data communication transmission program, adapted to effect a transmission of some or all of the stored data through a data transmission means to enable a further metal detector to receive and store for use in such further detector the said data.

The various embodiments herein provide a baby walker with braking mechanism to control a movement of the baby walker from moving into dangerous areas. The baby walker comprises a sensor unit, a wave transmitter system, a braking system and a power supply unit. The sensor unit is configured to sense an obstacle in the way of walker. The wave transmitter system, in communication with the sensor unit, is configured to generate signals on sensing the obstacle. The braking system, in communication with the wave transmitter, is configured to control movement of the walker upon reception of signals from the wave transmitter. The power supply unit is configured to supply electric power to the sensor unit, the wave transceiver the braking system.

A detector for fast neutrons has been developed which includes 1) selected open structure of solid hydrogen-containing material which converts impinging neutrons into recoil protons; 2) a surrounding gas which interacts with the protons to release electrons; 3) an electric field able to drift the electrons through and away from the open-structure material; and 4) an electron detector which monitors the drifted electrons thereby sensing the original impinging neutrons. This type of detector is advantageous for many applications, including efficient fast neutron detection; large area imaging of fast neutrons for fast neutron radiography; or fast neutron beam profiling.

Peptide antigens corresponding to amino acid residues 2-12, 1-12, 2-15 and 1-15 of parathyroid hormone (PTH), antibodies having an affinity to such peptide antigens and methods of producing the same. Such antigens, antibodies and methods producing the same according to the present invention are useful in determining bioactive intact PTH levels in serum, plasma, and / or cell culture media. Such antibodies further possess a high degree of species cross-reactivity, but substantially mitigated cross-reactivity to non-whole PTH peptide fragments and little to no recognition of the first amino acid residue of PTH.

A metal detector adapted to generate a transmit search signal and to receive a receive search signal, and to analyse such received search signal, wherein the detector is adapted to allow a selection of operating parameters for each of these functions, said selection being effected by the storage as data in a memory of such selection, characterised in that the detector is adapted to allow such stored data to be modified in accordance with data I an external store, further characterised in that there is a digital data communication transmission program, adapted to effect a transmission of some or all of the stored data through a data transmission means to enable a further metal detector to receive and store for use in such further detector the said data.

Peptide antigens corresponding to amino acid residues 2-12, 1-12, 2-15 and 1-15 of parathyroid hormone (PTH), antibodies having an affinity to such peptide antigens and methods of producing the same. Such antigens, antibodies and methods producing the same according to the present invention are useful in determining bioactive intact PTH levels in serum, plasma, and / or cell culture media. Such antibodies further possess a high degree of species cross-reactivity, but substantially mitigated cross-reactivity to non-whole PTH peptide fragments and little to no recognition of the first amino acid residue of PTH.

A method and apparatus for evaluating a bioaerosol sample is provided which includes detecting frequency and / or time resolution factors that allow discriminate between a plurality of signals emitted by the bioaerosol to selectively detect biological materials contained in the bioaerosol sample from materials of non-biological origin and potentially associated with a pathogenic bioaenosol.

A method and system for improved detection of analog signals, where the analog signals may be composed of one or more analog frequencies. In the method and system, an analog signal is received. A stream of data samples is created from the analog signal. Based on the stream of data samples, a confidence factor regarding the presence of the one or more analog signals is created. The confidence factor is created based upon a confidence factor calculated for each of the one or more analog frequency signals. The confidence factor calculated for each of the one or more analog frequency signals is calculated utilizing incremental energies associated with each of the one or more analog frequency signals.

An aerosolized fingerprint compositions for spraying onto a surface for the purpose of indentifying latent fingerprints that comprises about 1 to about 75% fingerprint dusting powder and about 25 to about 99% non-CFC propellant.

The various embodiments herein provide a baby walker with braking mechanism to control a movement of the baby walker from moving into dangerous areas. The baby walker comprises a sensor unit, a wave transmitter system, a braking system and a power supply unit. The sensor unit is configured to sense an obstacle in the way of walker. The wave transmitter system, in communication with the sensor unit, is configured to generate signals on sensing the obstacle. The braking system, in communication with the wave transmitter, is configured to control movement of the walker upon reception of signals from the wave transmitter. The power supply unit is configured to supply electric power to the sensor unit, the wave transceiver the braking system.

A method of compensating for motion artefact of a portion of a subject, wherein signal intensity data representing movement of the portion of the subject is recorded and plotted on a display means. The method includes selecting a region of interest (ROI) covering an edge of the moving portion, calculating and plotting data points representing the average signal intensity of the selected ROI at specific time instances, producing a smoothed curve representing the mean of the plotted data points. The method further includes measuring the difference between the plotted data points and the smoothed curve at particular time instances to produce a difference curve, detecting a set of critical points on the difference curve, and interpolating the detected set of critical points to form a curve of equal time intervals for subsequent processing.

A device and a method for optical measurement of a target, wherein the target is irradiated with radiation beam (15) and a measurement beam (27) is received from the target and detected. Commonly used absorbance, reflectance and fluorescence measurements do not provide adequate information in e.g. measuring small contents of sulphur compounds. The present solution provides a new Raman spectrometer which is suitable for mass applications. A target is activated with pulses of a laser diode (12). The Raman signatures are measured and integrated successively with a point detector (44). A Fabry-Perot interferometer (42) on the measurement path is successively controlled into corresponding pass bands. While high spectral resolution or range is not required it is possible to use small-sized and low cost components.