The invention discloses a kit for measuring apolipoprotein C2. The kit contains a reagent R1, a reagent R2 and a calibration product, wherein the reagent R1 is prepared from: a buffer solution, electrolyte, a surfactant, a reaction enhancer, a stabilizer and a preservative; the reagent R2 is prepared from: a buffer solution, goat anti-human apolipoprotein C2 antibody latex particles, electrolyte,a surfactant, a stabilizer and a preservative; and the calibration product is prepared from: a buffer solution, recombinant apolipoprotein C2, bovine serum albumin, mannitol and sodium azide. The apolipoprotein C2 kit adopts double liquid reagents, redissolving preparation is not needed, and the kit can be directly used after a bottle is opened. The obtained latex particles are good in stability,and the accuracy of the detecting result is greatly improved; residue glycosyl at the Fc terminal of the apolipoprotein C2 antibody is oxidized into a formyl group through the sodium periodate, the binding rate of the antibody is increased, the stability of the antibody is improved, an active area where the antibody and antigen are bonded is effectively protected, and the sensitivity and stabilityof the detecting reagents are improved.