The invention discloses a manufacturing process for a novel functional fabric. The manufacturing process mainly comprises the following steps: 1) water spraying of a dyed fabric for setting; 2) calendering before sizing; and 3) one-knife PU resin functional coating treatment: performing one-knife PU resin functional coating treatment on a calendered surface, wherein a functional coating comprises,by mass, 60-70 parts of two-component polyurethane resin, 25-30 parts of one-component polyurethane resin, 5-10 parts of AC glue, 1-3 parts of a silicon-series dry agent, 1-2 parts of a bridging agent and a solvent X, and the usage amount of the solvent X is added with the viscosity of a rubber compound of 15000 CPS as the criterion. According to the invention, a one-knife coating process is adopted, so the novel functional fabric has the functions of low water pressure, high moisture permeability and UV resistance, and further has the advantages of light weight, thinness, easy storage, comfortable wearing, reduced environmental pollution, etc.