The invention discloses a multi-temperature refrigerator based on a non-azeotropic working medium with a large slip temperature, including a compressor, an air-cooled condenser, a first heat exchanger, a second heat exchanger, a dry filter, a capillary tube, and a first evaporator , the first electric regulating valve, the first gas-liquid separator, the second evaporator, the second electric regulating valve, the third evaporator, the third electric regulating valve, the fourth evaporator, the fourth electric regulating valve and the second gas Liquid separator; the outlet port of the first evaporator is connected with the inlet port of the first gas-liquid separator, the outlet port of the fourth evaporator is connected with the second inlet port of the first heat exchanger, and the second inlet port of the first heat exchanger Two outlet ports are connected with the inlet port of the second gas-liquid separator; the second outlet port of the first gas-liquid separator is connected with the second inlet port of the second heat exchanger, and the second outlet port of the second heat exchanger is connected with the second outlet port of the second heat exchanger. The inlet end of the second gas-liquid separator is connected. The multi-temperature refrigerator solves the problems of large irreversible loss in a single cycle and inaccurate temperature control.