The application provides a roll-to-roll micro-contact printing positioning mechanism, which comprises a two-degree-of-freedom positioning platform installed on a table top of an optical
vibration isolation platform and a support provided with a
stamping roller; the two-degree-of-freedom positioning platform comprises two symmetrical support structures which are used for installing a printing roller 7 and adjusting the displacement of the printing roller and the
stamping force of the printing roller, a
voice coil motor 3 for driving the printing roller to move in the vertical direction or the horizontal direction is arranged at the two support structures of the platform, and the platform is fixedly connected with the printing roller through a center carrier 2002; the carrier is formed with a plurality of flexible
parallelogram mechanisms 2001 which are uniformly arranged at the periphery and are connected with the
voice coil motor to form a transmission mechanism; the plurality of flexible
parallelogram mechanisms of the transmission mechanism are combined into a transmission structure capable of providing two-directional freedom through superposition of elastic beams and in a single-stage series connection mode; and the application can realize higher resolution and quality of a printed image through the characteristics of high-precision positioning, large
stroke range and uniform
contact force of the mechanism.