The invention discloses a sodium-lithium-iron-manganese-based layered oxide material and a preparation method and application thereof. The chemical general formula of the material is Naa[LibFeCMnd]O2+[beta], and the space group of the layered oxide material has a corresponding structure of O3 phase. The oxygen ion variable valence layered oxide material is used for a positive electrode active material of a sodium ion secondary battery, during first-cycle charging, iron ions in crystal lattices lose electrons, the average valence state is increased from +3 valence to +4 valence, oxygen ions in the crystal lattices lose electrons, and the average valence state is increased from -2 to -1; during first-week discharge, oxygen ions with higher valence state obtain electrons again, then iron ions obtain electrons and are reduced, along with deep discharge, part of manganese ions obtain electrons, and the average valence state is changed from tetravalence to trivalence; and from the second week, iron ions, oxygen ions and manganese ions jointly participate in the reversible electron gaining and losing process in the charging and discharging process.