The research is different from other previous researches, and the action mechanism of the
astragalus flavone extract for treating the type 2
diabetes mellitus is discussed by applying a biological method.
Skeletal muscle cells are taken as experimental subjects, an experimental group for blocking a P13 / Akt
signal channel is constructed, then the
astragalus flavone extract is given, liver
cell related
carbohydrate gene expression is analyzed, and the
cellular mechanism of the
astragalus flavone extract for treating type 2
diabetes mellitus is discussed. At present, the research is not reported at home and abroad. Therefore, a
novel treatment method is provided by the astragalus flavone extract. By using the method, lots of expenditures for
purchasing db / db mice and double-
gene knockout mice can be saved. According to the research, the
protein expression level of an
insulin receptor substrate P-IRS-1 is measured, then the influence of the astragalus flavone extract on the
insulin sensitivity of mouse myoblasts (C2C12) is detected, and a theoretical basis is provided for treatment of type 2
diabetes mellitus.