Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
Hiro

53 results about "Phenotype correlation" patented technology

A correlation between the nature or the location of a mutation in an individual based on observations of affected individuals and their respective genotype. GENOTYPE-PHENOTYPE CORRELATION: "The genotype-phenotype correlation are used to elucidate affects of mutation.". Related Psychology Terms.

A method or system for identification of a causative mutation causing a phenotype of interest in a test sample

A method for identifying a mutation associated with a phenotype of interest in a non- vascular plant, wherein the method comprises (a) aligning the DNA sequence of a reference DNA sequence and identifying a first set of sequence mismatches between the two sequences; wherein the test sample is from a mutagenized non-vascular plant; (b) aligning the DNA sequence of at least one comparison sample to the reference DNA sequence and identifying a second set of sequence mismatches between the two sequences; (c) filtering the first set of mismatches with respect to the second set of mismatches to identify a subset of mismatches that are unique to the first set of mismatches, wherein the subset of mismatches are candidate mutations for the causative mutation; wherein the test sample is from a non-vascular plant exhibiting the phenotype of interest and wherein the at least one comparison sample is from an independent non- vascular plant of the same genus that does not exhibit the phenotype of interest; and wherein the reference DNA sequence is a known reference sequence for a non-vascular plant of the genus. In addition, a method for identifying a mutation associated with a phenotype of interest in a non-vascular plant, wherein the method comprises a) aligning the DNA sequence of a reference DNA sequence and identifying a first set of sequence mismatches between the two sequences; wherein the test sample is from a mutagenized non-vascular plant; (b) aligning the DNA sequence of at least one comparison sample to the reference DNA sequence and identifying a second set of sequence mismatches between the two sequences; (c) filtering the first set of mismatches with respect to the second set of sequence mismatches to identify a subset of mismatches that are common to the first and second sets of sequence mismatches wherein the test sample and the comparison sample(s) are from independent non-vascular plants exhibiting the phenotype of interest and wherein the independent non-vascular plants are the same genus; and wherein the reference DNA sequence is a known reference sequence or a non-vascular plant of the genus or a non-vascular plant of the genus.
Owner:OXFORD UNIV INNOVATION LTD

Medical gene analysis method and system

The invention relates to a medical gene analysis method. The method comprises the steps of obtaining individual variation gene information, wherein the individual variation gene information comprisesmulti-site information; selecting a phenotype and inputting the multi-site information and a correction parameter; querying a genotype and phenotype correlation database to obtain a first relationshipvalue of the phenotype correspondingly selected by the multi-site information, and according to the first relationship value and a preset rule, calculating a second relationship value of the individual variation gene information and the corresponding phenotype; querying multiple third relationship values of multi-reference individual variation gene information limited by the correction parameterand the corresponding phenotype in a genotype and phenotype user database, and calculating an average value; and according to a comparison result of the second relationship value and the average valueof the third relationship values, outputting a phenotype assessment result corresponding to the individual variation gene information. The invention furthermore provides a medical gene analysis system. The medical gene analysis method and system can meet the prediction demand of a user on own gene and phenotype relationships.
Owner:GUANGZHOU KANGXINRUI GENE HEALTH TECH CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products