The invention discloses an air conditioner, a vehicle and a cleaning method of the air conditioner, the air conditioner comprises a box body, a first air duct, a second air duct, a
communicating cavity, an inner circulating air port, an outer circulating air port and an in-vehicle air outlet are formed in the box body, the first air duct is connected between the outer circulating air port and the
communicating cavity, and the second air duct is connected between the
communicating cavity and the in-vehicle air outlet; the second air duct is connected with the inner circulation air opening and communicates with the communicating cavity, and the in-vehicle air outlet is connected with the communicating cavity. The
evaporator is arranged in the first air duct; at least part of the heater is arranged in the second air duct; the air conditioner has a cleaning mode, and in the cleaning mode, air in a vehicle enters the second air duct through the inner circulation air opening, enters the first air duct through the communicating cavity after being heated by the heater, cleans the
evaporator and then is exhausted through the outer circulation air opening. According to the air conditioner, high-temperature sterilization of the
evaporator can be achieved, it is avoided that breeding of
mildew,
bacteria and the like affects the health and use experience of a user, and the attractiveness and market competitiveness of a vehicle are improved.