The invention relates to a cleaning device, in particular to a medical scalpel cleaning device. The technical problem to be solved is to provide a medical scalpel cleaning device which can thoroughlysterilize and disinfect the scalpel, is convenient and simple to clean and can reduce labor. The medical scalpel cleaning device comprises a box body, a water tank, a disinfection box, a water outletpipe, a first valve, a first fixing plate, a net frame, a strip-shaped spray head, a motor, a sealing partition plate, a first bearing seat and the like; the water tank is arranged at the left wall ofthe box body, the disinfection box is arranged at the inner side of the lower wall of the box body, the water outlet pipe is connected at the lower part of the right wall of the disinfection box, thefirst valve is arranged on the water outlet pipe, and the inner side of the rear wall of the box body is left-and-right symmetrically provided with a first fixing plate. The effect of thorough sterilization and disinfection, convenient and simple cleaning, reduced labor is achieved, a guide rod and a guide hole guide an electric heating lamp to move up and down, the electric heating lamp can be prevented from shaking randomly, disinfectant is rotated inside the disinfection box, and the scalpel can be more thoroughly sterilized and disinfected by the disinfectant.