42results about How to "Easy and accurate diagnosis" patented technology

The invention relates to a residual network rolling bearing fault diagnosis method based on time-frequency analysis. The method comprises the following steps of S1. collecting vibration signal data, converting a vibration time domain signal of a rolling bearing into a time-frequency map by using short-time Fourier transform, and converting the time-frequency map into a two-dimensional gray level time-frequency map; and S2. performing feature extraction on the signal by using a residual network, and diagnosing a fault type of the bearing, wherein the input of the residual network is the gray level time-frequency map generated in the step S1, and the output of the residual network is a fault diagnosis result. According to the residual network rolling bearing fault diagnosis method provided by the invention, the bearing vibration data are converted into the time-frequency map by using the short-time Fourier transform, the time domain and frequency domain features during the vibration of afaulty bearing can be clearly reflected, and the network can accurately diagnose different fault types conveniently. Since the time-frequency signal contains both the time domain and frequency domaininformation of the bearing, and the deepening of a network layer of the residual network does not cause the problem of gradient disappearance or gradient explosion, higher accuracy can be obtained bythe method while performing fault diagnosis on the bearing.

The invention discloses a crop disease spore capturing, separating and detecting device. The crop disease spore capturing, separating and detecting device comprises a collecting box, an electric control box, a sampling opening and a capturing channel, wherein the sampling opening for introducing disease spores is formed in the upper surface of the collecting box; the bottom of the collecting box is communicated with the capturing channel; a collecting adhesive tape for capturing the spores is arranged in the capturing channel; the collecting adhesive tape is driven by electric wheels at two ends to transmit; the electric control box is arranged on the right side of the collecting box and the capturing channel; a fan, an electric control module of the electric wheels and a microscopic imagecollecting module are arranged in the electric control box; the fan is arranged on the side wall of a box body of the collecting box and the capturing channel; and a directional air source is generated to drive the spores in the collecting box to be uniformly separated and settled to the collecting adhesive tape. The device separates the spores captured in the collecting box, so that the spores are uniformly settled to the collecting adhesive tape with a hollow design, and mutual stacking of collected materials is avoided; and by the advantages of small size, light weight and the like, the crop disease spore capturing, separating and detecting device can be mounted under an unmanned aerial vehicle, a large space monitoring range is covered, and the application prospect is wide.

The invention discloses a glioma diagnosis and prognosis marker circ16:85633914|85634132 and application. A reagent for detecting annular RNAcirc16:85633914|85634132 sourced from brain tissues is usedfor preparing a diagnosis and prognosis preparation of glioma patients. The research shows that the expression of the RNA circ16:85633914|85634132 in the brain tissues of the glioma patient is apparently reduced compared with the normal brain tissues, and the ROC curve analysis shows that the RNA circ16:85633914|85634132 has relatively high diagnosis performance for the glioma. Meanwhile, the patient with relatively high expression of the circ16:85633914|85634132 has higher post-operative survival rate. The diagnosis analysis and prognosis determination can be made for the glioma high risk group by detecting the annular RNA circ16:85633914|85634132 in the glioma tissues of the glioma patient.

The invention belongs to the biotechnology field, and discloses a glioma prognostic marker hsa_circ_0021827 and application. In the invention, it is firstly found that the expression level of hsa_circ_0021827 in the serum exosome of a glioma patient is obviously increased compared with a control group (p is equal to 0.025), and ROC analysis shows that the glioma prognostic marker hsa_circ_0021827has a relatively high diagnostic value for a glioma (AUC is equal to 0.823, P is equal to 0.003, the sensitivity is 70% and the specificity is 90.9%). Therefore, an early-stage rapid non-invasive diagnosis of the glioma patient can be made by detecting the expression level of hsa_circ_0021827 in the serum exosome of the glioma patient.

The present invention relates to methods and compositions of a novel gene and the peptide encoded by the gene. Mutations in the gene, named atlastin, are factors in the disease Hereditary Spastic Paraplegia and related disorders. The present invention will be used for the in the research, diagnosis and treatment of these disabling diseases.

The invention discloses a glioma prognostic marker Circ6:4891713|4892379 and applications. The fact that the exosome secreted by glioma cells has obvious accumulation on circ6:4891713|4892379 is firstly found; the expression level of circ6:4891713|4892379 in serum exosome of patients with glioma is found to be obviously increased compared with a normal control group (p=0.0005), ROC analysis showsthat circ6:4891713|4892379 has extremely high diagnosis value on glioma (AUC=0.906, p=0.001, and sensitivity and specificity are respectively 70.8% and 100%). Therefore, the early-phase and rapid non-invasively diagnosis on the patients with glioma can be made by detecting the expression level of circ6:4891713|4892379 in serum exosome of patients with glioma.

The invention belongs to the technical field of biology and discloses a glioma diagnostic marker circ7:100812747|100813208 and application. In the invention, exosomes secreted by glioma cells are found to have an obvious enrichment effect on the circ7:100812747|100813208 for the first time; meanwhile, the expression level of the circ7:100812747|100813208 in serum exosomes of glioma patients is found to be remarkably improved compared with that of a control group (p is equal to 0.0444); ROC (Receiver Operating Curve) analysis shows that the circ7:100812747|100813208 has higher diagnostic value(AUC is equal to 0.924, p is equal to 0.001, and the sensitivity and the specificity are 83.3 percent and 87.5 percent respectively) to glioma. Therefore, early rapid noninvasive diagnosis of the glioma patients can be realized by detecting the expression level of the circ7:100812747|100813208 in the serum exosomes of the glioma patients.

The invention relates to the technical field of biological genes and particularly relates to a primer for amplifying related genes of a breast cancer and an ovarian cancer.The primer is shown by a sequence 1-36 in a sequence table.In application of the primer and a kit in amplification of the related genes of the breast cancer and the ovarian cancer, seven related genes including a coding sequence of each gene of the breast cancer and the ovarian cancer can be simultaneously detected, and the detection saves time and is efficient.A tumor paraffin-embedded tissue slice is adopted for DNA extraction, sample obtaining is easier, and sample variety is more advantageous to achievement of accurate diagnosis.The domestic self-dependently innovated kit is developed, instead of dependency on reagents/kits of foreign companies.The detection cost is remarkably reduced, and it is expected that the detection cost is reduced by 90% compared with the commercially-available prior art.

The invention belongs to the biotechnology field, and discloses a glioma prognostic marker circ1:29154696|29154910 and application. In the invention, it is firstly found that the expression level of circ1:29154696|29154910 in the serum exosome of a glioma patient is obviously increased compared with a control group (p=0.01), and ROC analysis shows that the glioma prognostic marker circ1:29154696|29154910 has a relatively high diagnostic value for a glioma (AUC=0.911, P=0.002, the sensitivity being 75% and the specificity being 98%). Therefore, an early-stage rapid non-invasive diagnosis of theglioma patient can be made by detecting the expression level of circ1:29154696|29154910 in the serum exosome of the glioma patient.

The invention belongs to the biotechnology field, and discloses a glioma prognostic marker circ7:73686636|73687095 and application. In the invention, it is firstly found that the expression level of circ7:73686636|73687095 in the serum exosome of a glioma patient is obviously increased compared with a control group (p is equal to 0.0012), and ROC analysis shows that the glioma prognostic marker circ7:73686636|73687095 has a relatively high diagnostic value for a glioma (AUC is equal to 0.872, P is equal to 0.001, the sensitivity is 76.5% and the specificity is 90.9%). Therefore, an early-stagerapid non-invasive diagnosis of the glioma patient can be made by detecting the expression level of circ7:73686636|73687095 in the serum exosome of the glioma patient.