The invention discloses an auxiliary method for clinical early detection of digestive tract tumors. The auxiliary method comprises the following steps: S1, preparing before operation; S2, cleaning before examination; S3, relieving pain; S4, scanning; S5, examining; S6, completing examination; S7, extracting serum for later use; S8, measuring; S9, measuring and color comparison through a reagent; and S10, carrying out protein chip detection. Two auxiliary detection methods combining endoscopy and serum detection are adopted, the coincidence rate of detection is 93% or above, and a method of photo preservation is adopted to facilitate follow-up viewing, and moreover, the detection cost is low. Compared with an existing clinical early detection method for digestive tract tumors, the method has the advantages that the positive rate of a C-12 protein chip on detection of the digestive tract tumors is 62.9%-94.12%; and by analyzing the content of 12 common tumor markers in serum, clinical detection is assisted, and meanwhile, staging of disease course, tracking of curative effect, analysis of prognosis and follow-up visiting are facilitated.