The embodiment of the invention provides a mask frame assembly and a manufacturing method thereof, and relates to the technical field of evaporation. The problems that in the prior art, mask sheets are wrinkled and warped, howling strips and cover strips are replaced or repaired, consequently, cost is increased, the relative positions of the howling strips, the cover strips and the mask sheets cannot be adjusted, and a mask frame assembly cannot be cleaned up can be solved. The mask frame assembly comprises a first frame, a second frame, multiple mask sheets and cover strips and/or howling strips. The first frame and the second frame are each provided with a hollow area and are fixedly connected in a sleeved manner. The multiple mask sheets are sequentially arranged on the hollow area of the first frame in a crossing manner, and the two opposite ends of each mask sheet are fixed to the first frame. The cover strips and/or howling strips are arranged on the hollow area of the second frame in a crossing manner, and the two opposite ends of each cover strip and/or howling strip are fixed to the second frame. The cover strips are located at the clearance positions between the adjacentmask sheets, and the howling strips cross over invalid mask areas of the multiple mask sheets so as to support the multiple mask sheets.