The invention discloses a
traditional Chinese medicine compound preparation for treating
migraine and a preparation method thereof. The
traditional Chinese medicine compound preparation comprises the following pharmaceutical raw materials: 1-20 parts of Szechuan lovage
rhizome, 1-20 parts of dahurian
angelica root, 1-20 parts of peppermint, 1-20 parts of oriental waterplantain
rhizome, 1-20 parts of fineleaf
schizonepeta herb and 1-20 parts of largehead atractylodes
rhizome, and the part ratio is weight ratio.
Ethanol is adopted for extracting active ingredients of the Szechuan lovage rhizome and the dahurian
angelica root; and the
steam distillation method is adopted for extracting volatile oil of the peppermint, the oriental waterplantain rhizome, the fineleaf
schizonepeta herb and the largehead atractylodes rhizome, and water is further adopted for extracting other active ingredients. Extract solution of the six medicines are concentrated and dried; and the volatile oil is included via beta-
cyclodextrin and uniformly mixed with extracts after
drying, excipients are added, and a preparation is finally prepared. The
medicine has good
analgesic effect and can also be antagonistic to shrinkage role of PE (
polyethylene) and 5-HT (5-hydroxytryptamine) to blood vessels, improve the
diameter of capillary blood vessels, improve the
microcirculation and effectively improve the
cerebral blood flow of rats, thereby being an effective prescription for treating the
migraine and Meniere'
s syndrome.