The invention provides a production process of low weight middle partition paper. The production process comprises the following steps: burdening, disintegrating, screening and purifying, concentrating, pulping, pulp preparing, flowing, forming, compound squeezing, drying, surface sizing, and coiling. In the burdening step, based on fiber quality and impurity content, OCC waste paper of differentgrades is matched according to the determined raw material ratio of a product; wherein the OCC waste paper comprises domestic waste paper and imported waste paper accounting for 10-30% of the total weight, and the imported waste paper comprises American waste paper, European waste paper and Hong Kong waste paper. Main physical indexes of the low weight middle partition paper produced by the production process are as follows: quantifying (60-65) +/-3g/m<2>; the tightness is greater than or equal to 0.50 g/cm<3>; the transverse ring crush index is greater than or equal to 3.0 Nm/g; the longitudinal breaking length is larger than or equal to 3.5 km, the water content is 7.5%-10.0%, and the water absorption is smaller than or equal to 50 g/m<2>. On the premise that the strength index of the product meets the use purpose, the quantification of the middle partition paper product is reduced as much as possible, under the condition of the same weight, the use area of the product is remarkablyincreased, and therefore development of low-carbon economy can be promoted.