The invention relates to a startup and shutdown circuit which comprises a startup key, a startup delay circuit, a startup buffer circuit, a startup and shutdown enabling circuit, a power circuit, a startup level locking circuit, a shutdown detection circuit and a singlechip control circuit, wherein the startup key, the startup delay circuit, the startup buffer circuit and the startup and shutdown enabling circuit are sequentially connected; the startup and shutdown enabling circuit is connected with the power circuit; the power circuit, the startup level locking circuit and the startup delay circuit are sequentially connected; the power circuit is further connected with the startup buffer circuit; and the shutdown detection circuit, the singlechip control circuit and the startup and shutdown enabling circuit are sequentially connected. The startup and shutdown circuit is applicable to a multi-parameter monitor, improves the system stability through hardware startup and software shutdown, has the advantages of simplicity, stability, low standby current, low energy consumption, flexible design and the like, and greatly improves a use effect of a user.