The invention belongs to the technical field of organic substance extraction, and discloses a novel extraction method of total flavonoids in
Senecio scandens. The method comprises the steps of conducting cleaning, disinfection,
drying and pulverizing on the above part of fresh
Senecio scandens root, conducting sieving by a 20 mesh
sieve to obtain a
Senecio scandens
powder; putting the
Senecio scandens powder in a 60%
ethanol solution, conducting immersing for 1 hour, and conducting ultrasonic extraction for 40 min under conditions of 350 W and 80 DEG C; after ultrasonication, taking out the solution, conducting suction
filtration, retaining the filtrate, immersing the filter residue in 70%
ethanol for 1 hour and then conducting vacuum suction
filtration; merging the two filtrates, conducting
centrifugation to obtain a supernatant, conducting concentration to volatilize off remaining
ethanol to obtain a
flavonoid extract concentrate; and conducting lyophilization to obtain a lyophilizedpowder, that is, the total flavonoids in
Senecio scandens. The method of the invention adopts an ultrasonic extraction method to extract total flavonoids in
Senecio scandens, the detection process issimple, the extraction rate is high, the extraction speed is fast, and the problem of long-time
reflux extraction in a traditional extraction process is avoided.