The invention relates to a rapid clamping drive plate. The rapid clamping drive plate comprises a clamping drive plate body, clamping jaws and an eccentric compression bar, wherein a circular hole for arranging a workpiece is axially arranged on the clamping drive plate body, two rectangular grooves are symmetrically installed on the end surface of the clamping drive plate body, the clamping jaws are installed in the rectangular grooves of the clamping drive plate body respectively through forcing screws, a semicircular groove is arranged on the lower portion of the clamping drive plate body, the eccentric compression bar is arranged in the semicircular groove of the clamping drive plate body through a hinge pin, the front end surfaces of the clamping jaws and the front end surface of the eccentric compression bar form three-point support in the circular hole circumference of the clamping drive plate body, the eccentric compression bar is rotated to press the workpiece tightly, and the workpiece arranged in the circular hole is clamped. During usage, when a spindle of the machine tool rotates, one side surface of the eccentric compression bar contacts a drive rod arranged on the machine tool, and the drive rod presses the eccentric compression bar to enable the workpiece to be clamped more tightly, therefore rotation is achieved. The rapid clamping drive plate has the advantages of being reasonable in structure, simple to manufacture, convenient to operate, low in labor intensity, reliable in clamping, and suitable for clamping of shaft diameters in different sizes.