The invention provides a manufacturing method of a touch screen with an IR induction zone, and belongs to the technical field of touch screens. The problems that in the prior art, process steps are complex and the manufacturing cost is high are solved. The manufacturing method of the touch screen with the IR induction zone includes the steps of A, preliminarily machining a glass cover plate, wherein the glass cover plate is selected, a display zone and a non-display zone are designed on the back face of the glass cover plate, and a black ink layer is attached to the non-display zone; B, curing the black ink layer, wherein the glass cover plate manufactured in the step A is baked; C, manufacturing the IR induction zone, wherein the IR induction zone is designed in the non-display zone on the back face of the glass cover plate and subjected to laser etching treatment, namely, a plurality of small round light-transmitting holes are etched in the black ink layer in the IR induction zone, and a touch screen with the IR induction zone is preliminarily formed; D, performing discharging, wherein the manufactured touch screen is cleaned, and the finished product is discharged. According to the manufacturing method, only a few steps are needed, time is short, material consumption of the manufacturing process is small, and cost is low.