The invention discloses a boiler combustion optimization system, method and device based on data driving and intelligent algorithm. The optimization system comprises a data management system, an intelligent optimization system and a display system, wherein an optimal operation mode of each working condition is obtained by carrying out data mining on a large amount of historical operation data, andan optimal case knowledge base containing boiler operation characteristics and laws is built. Operation real-time data of a boiler are optimized through the intelligent optimization system, a combustion optimization instruction is obtained, transmitted to the display system for display, and fed back to a control system. According to the system, method and device, existing data resources are fullyutilized, the optimal adjustment of the combustion instruction is realized, and the technical problems that the boiler is likely to operate in a non-optimal operation curve range in an existing control system can be solved.