The utility model discloses a slide rail with protection structure, including connecting rod, both sides of connecting rod all install the bottom plate, and the bottom end of bottom plate installs the support leg, and the inside setting of bottom plate includes telescopic slot, and the bottom of telescopic slot sets up fixed screw, and the bottom of fixed screw installs the rotating block. The utility model discloses a base is installed to both sides of connecting rod, and connecting rod can slide in the inside telescopic slot, therefore, the base can slide along connecting rod, and the position of the side plate of top end can be adjusted when the base slides, and the distance between side plate can be adjusted when the position of side plate is adjusted, and the position of side plate can be adjusted to make side plate adapt to different situations, and different objects can slide in the inside side plate, when needing to fix the base, can twist rotating block and drive fixed screw to fix, and the base can be fixed when fixed screw is tightened, to reach the purpose that slide rail is convenient to adjust width like this.