The invention discloses a tube-shell type heat exchanger with a super-hydrophobic/hydrophilic surface. The tube-shell type heat exchanger comprises a shell, a first tube plate, a second tube plate, afirst end socket, a second end socket, and a heat exchange tube bundle arranged in the shell. The heat exchange tube bundle communicates with an inner cavity of the first end socket and an inner cavity of the second end socket. A patterned surface in a certain geometrical shape covers the surface of the heat exchange tube bundle, and super-hydrophobic areas and super-hydrophilic areas are distributed on the patterned surface at intervals. A first wave-shaped transverse plate and a second wave-shaped transverse plate which are arranged in parallel in the length direction and staggered by a certain distance are arranged in the shell. A baffle plate is arranged between the first wave-shaped transverse plate and the second wave-shaped transverse plate. The tube-shell type heat exchanger is simple in structure and easy to maintain, by the adoption of the super-hydrophobic/hydrophilic surface coating structure, the heat transfer coefficient of the tube bundle can be remarkably increased, andthe heat transfer effect is reinforced; and meanwhile, the pressure drop and flowing resistance are reduced to the greatest extent, flowing dead zones are eliminated easily, the heat exchange area isincreased, the heat exchange efficiency is improved, and the tube-shell type heat exchanger is resistant to high temperature and high pressure, even in heat exchange and good in stability.