The invention discloses a ventilation pipeline capable of preventing particles from entering the interior to precipitate and accumulate. The ventilation pipeline comprises an air inlet pipe, a flange is arranged at the lower end of the air inlet pipe, a connecting pipe is arranged at the lower end of the flange, a machine box is fixedly connected to the upper end of the left side of the air inlet pipe, a rotating motor is arranged at the upper end of an inner cavity of the machine box, the output end of the rotating motor is fixedly connected with a power rod, the lower end of the power rod penetrates through the air inlet pipe and is provided with a driving gear in a sleeved mode, and a transmission rod is arranged below the driving gear. According to the ventilation pipeline, through the arrangement of a filter screen, filtering can be carried out on circulating air, so that the phenomenon that dust enters a bent part to cause accumulation and blockage is avoided; and through the arrangement of the machine box, the rotating motor, the power rod, the driving gear, a cleaning brush, a dust discharging opening, a driven gear and the transmission rod, and cleaning can be automatically carried out on the surface of the filter screen, so that dust is prevented from being gathered on the surface of the filter screen to influence air circulation, and cleanness and circulation of the interior of the air inlet pipe are effectively kept.