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Method and Apparatus to Compensate for Melanin and Hemoglobin Variation in Determination of a Measure of a Glycation End-Product or Disease State Using Tissue Fluorescence

A method of determining a measure of a tissue state (e.g., glycation end-product or disease state) in an individual is disclosed. A portion of the skin of the individual is illuminated with excitation light, then light emitted by the tissue due to fluorescence of a chemical with the tissue responsive to the excitation light is detected. The detected light can be combined with a model relating fluorescence with a measure of tissue state to determine a tissue state. The invention can illuminate the skin and detect responsive light over a time that spans a plurality of cardiac cycles of the individual, which can, as an example, help mitigate the effects of time-varying signals such as those due to hemoglobin. The invention can also determine the amount of light to be directed to the skin, for example by controlling the time that a light source is energized. The amount of illumination light can be determined from a skin reflectance characteristic such as pigmentation or melanin in the skin. Controlling the amount of light directed to the tissue can reduce the dynamic range required of a corresponding optical system, for example by allowing a single system to accurately measure individuals with very light skin and individuals with very dark skin.
Owner:VERALIGHT INC

Apparatus and method for issue grouping of instructions in a VLIW processor

An apparatus and method for issue grouping of instructions in a VLIW processor is disclosed. There can be one, two, or three issue groups (but no greater than three issue groups) in each VLIW packet. In one embodiment, a template in the VLIW packet comprises two issue group end markers where each issue group end marker comprises three bits. The three bits in the first issue group end marker identifies the instruction which is the last instruction in the first issue group. Likewise, the three bits in the second issue group end marker identifies the instruction which is the last instruction in the second issue group. Any instructions in the VLIW packet falling outside the two expressly defined first and second issue groups are placed in a third issue group. As such, three issue groups can be identified by use of the two issue group end markers. In one embodiment, the template of the VLIW packet includes a chaining bit. The chaining bit is used to "chain" instructions appearing after the last instruction of the last issue group of a first VLIW packet to the instructions in the first issue group of a second VLIW packet. In one embodiment, a mask generation logic along with other logic blocks are utilized to generate an appropriate mask. The generated mask is used to pass through instructions in a VLIW packet which belong to a same issue group for execution in a same clock cycle.
Owner:CALLAHAN CELLULAR L L C
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