The invention discloses a novel-structure horizontal machining center machine tool in the field of horizontal machining centers. The machine tool comprises a base, a stand column, a spindle box and a sliding saddle, a stress part is arranged at the upper end of the base, the stand column is fixedly mounted above the stress part, a reinforcing rib is arranged below the stress part, the sliding saddle is slidably mounted on the left end face of the stand column, the spindle box is slidably mounted on the front end face of the sliding saddle, and the sliding saddle controls the spindle box to move through a lead screw part in front of the sliding saddle. By means of the structure, the problems that due to the fact that a conventional horizontal machining center lathe bed is complex in structure, supporting ribs in a base are distributed in a net shape, casting difficulty is higher, the overall area of the base is larger, the number of lathe bed foundations is large, the installation and debugging process is complex, time and labor are wasted, a huge structure and low rigidity in the X axis direction exist in stand column and sliding saddle hollow frame type horizontal machining, a three-axis lead screw bearing of a traditional horizontal machining center usually selects an angular contact ball bearing, the bearing needs to be used in a matched manner, the number of bearings is large, installation accessories are many and complex, and installation is tedious exist are solved.