The invention relates to the technical field of gluing, in particular to an automatic colloidal coating gluing mechanism suitable for plastic plates. The automatic colloidal coating gluing mechanism comprises a base and a processing table, and further comprises a controller, a feeding device, an impurity removal device and a spraying device, the feeding device comprises a lifting plate, a jacking assembly and a pushing assembly, and the impurity removal device comprises a rolling brush and a traction assembly; and the spraying device comprises a spray head, an extrusion assembly and a sliding assembly, a top plate is fixedly arranged at the top of the base, the sliding assembly is arranged at the bottom of the top plate, the spray head and the extrusion assembly are both arranged on the sliding assembly, and the jacking assembly, the pushing assembly and the extrusion assembly are electrically connected with the controller. The plates are prevented from being clamped effectively, and feeding efficiency is high; and meanwhile, the gluing surface can be cleaned before gluing, smooth gluing is guaranteed, bubbles are prevented from being generated, and it is guaranteed that follow-up products adhere to the gluing surface firmly.