The invention relates to a novel convenient and portable insect poison bottle which is integrally in a cuboid shape and mainly comprises an insect cylinder, a poison chamber and a cylindrical channel. The insect tank is of large, medium and small specifications, the top of the insect tank is movably connected with a tank bottle cap, a vertical partition plate on the right side of the large tank is connected with the left sides of the small insect tank, the middle insect tank, the airflow chamber and the poison chamber, the small insect tank, the airflow chamber and the middle insect tank are sequentially arranged from back to front, and the poison chamber is arranged on the lower side. And the right side of the airflow chamber is connected with the cylindrical channel. The cylindrical channel comprises a threaded bottle cap, a control knob, a semi-arc net-shaped partition plate and a semi-arc solid plate, and the control knob is rotated to control whether poison gas enters the insect tank from the airflow chamber or not. And the poison chamber is provided with a side bottle opening. The device is reasonable in structure, convenient to carry and high in practicability, can meet the requirements of insects of different types and sizes, and can solve various coexisting problems of one chamber of insect poison, difficulty in adding fumigant and cleaning, poison gas leakage and the like.