The invention provides a tool rest cooling structure for a machine tool, and belongs to the technical field of machine tool machining. According to the tool rest cooling structure for the machine tool, a flow guide hole penetrating through the two ends and a nozzle and a connection joint which are arranged at the two ends of the flow guide hole are formed in a cutter pressing block; the connection joint is connected with a cutting fluid feeding pipe; a spray head of the nozzle faces a cutter head of a cutter; the existing cutter pressing block structure is fully used as a conveying pipeline, cooling of a machined position and blowing-away operation of sweeps are achieved, cost is reduced, the conveying stroke of cutting fluid is only the width of a tool apron within the range of the tool apron, and the conveying stroke is shortened; and meanwhile, the pressure bearing capacity is better, pipeline bending is not needed, the deformation and dislocation problems are avoided, the structural strength is higher, the shaking problem in the using process is avoided, stability is better, adjustment only needs to be conducted once in the initial installation process, the problems of inconvenience and heavy workload caused by subsequent repeated adjustment are avoided, the arrangement space is saved, the installation limitation is small, the adaptability is higher, and the use performance of the machine tool is improved easily.