The present invention relates to the technical field of medical devices, in particular to a disposable liquid collection device, which includes a liquid storage tube and a liquid guiding device, the liquid storage tube includes an opening and a liquid storage cavity, and the liquid guiding device is provided with a liquid guiding channel and a liquid guiding device. An annular side wall, one end of the liquid guiding channel is a liquid inlet, the other end is a liquid outlet, and a one-way valve is also included. The one-way valve includes a hollow valve cover and a valve pivotally connected to the inner wall of the valve cover. The inner wall is fixed with a push plate, the liquid diversion device is detachably installed on the upper part of the valve cover, and the liquid storage pipe is detachably installed on the lower part of the valve cover, the push plate overlaps with the valve partially or completely, and the rotating liquid guides device, the push plate pushes the valve down to close the valve cover. Compared with the prior art, the disposable liquid collection device of the present invention collects the urine in the liquid storage tube, and the one-way valve on the liquid storage tube prevents the urine from leaking. Leakage and backflow, simplified structure, cost saving, simple and hygienic operation, and convenient for patients to use.