The invention discloses an air-conditioning device capable of realizing gradient utilization for waste heat of a ship. The air-conditioning device comprises a heat pump system, an organic Rankine cycle (ORC) system, a seawater cycle system, an air-conditioning terminal system, a smoke pipeline system, a motor, a power generator and a rotary shaft switcher. According to the air-conditioning device disclosed by the invention, a previous utilization manner for waste heat of a diesel engine of a ship is changed, and ORC and a heat pump technology are coupled to realize the gradient utilization for the waste heat, that is, high-temperature smoke drives the ORC system at first, then enters a single-stage waste heat boiler, and finally carries out heat exchange and heating; and a turbine of the ORC system drives a compressor and the power generator, and an effect of 'cold, heat and electricity' cogeneration is achieved. The ORC system, the heat pump system and the seawater cycle system are cooperated, and in a high-temperature environment, a condensation temperature of a refrigerant is lowered by deep low-temperature seawater, so that the problem of poor refrigeration performance of an air conditioner of the ship is solved; and in a low-temperature environment, an evaporation temperature of the refrigerant is raised through condensation heat of an organic working medium, so that the problem of poor heating performance of the air conditioner of the ship is solved. Utilization efficiency for the waste heat of the diesel engine is increased through the gradient utilization for the waste heat of the smoke, so that economical efficiency and energy conservation are achieved.