The invention discloses a preparing method for low-irritability infant nutritive rice flour. The preparing method includes the steps that organic rice serves as a main raw material, and smashing, screening, pulp mixing, stirring and ultrasonic treatment are conducted; a pH value of pulp is adjusted, trypsin and neutral protease are added, centrifugation is conducted, supernatant is filtered with an ultrafiltration membrane, a solution being smaller than 10 kDa and centrifugal solid are mixed and stirred, the pH value of the pulp is adjusted again, and mesophilic alpha-amylase is added for enzymolysis; the mixture is subjected to roller drying to obtain rice slices, cured grain powder, fruit powder, whole milk powder, soy isolate protein, concentrated whey protein, maltodextrin, fructo-oligosaccharide, galactooligosaccharide, probiotics, mineral substances and multivitamins are added, and are ground and mixed evenly, and sterilization and filling are conducted. The low-irritability infant nutritive rice flour prepared with the method is used for infants of 6 months or above to eat, the problems that an ingredient is single, functional ingredients are insufficient, polypeptide is bitter, the taste is poor, and digestion is difficult are solved, the immunity can be improved, sensitization is reduced, and the rice flour has wide application in the infant food field.