121 results about "Blood gase" patented technology

A method and apparatus for the transcutaneous monitoring of blood gases generally comprises a blood gas data acquisition device, a vacuum source and a blood gas transducer unit. The blood gas transducer unit is adapted for application to a patient's skin and administration of a local vacuum at the area of patient application. It further comprises an electrochemical blood gas transducer, well known to those of ordinary skill in the art, which is disposed entirely within the local vacuum at the area of patient application. The vacuum source is placed in fluid communication with the blood gas transducer unit, through a hydrophobic membrane filter for safety purposes, in order to induce a condition of hyperperfusion in the locality of the electrochemical blood gas transducer. Under the control of a microcontroller, or equivalent means, the blood gas acquisition device is then utilized to capture a measure of skin surface oxygen or carbon dioxide pressure. The microcontroller can then utilize this measure to arrive at an estimate of arterial partial pressure of oxygen or carbon dioxide, accordingly. Because vacuum induced perfusion produces the requisite condition of hyperperfusion without local heating and, therefore, without acceleration of the local metabolic function, the present invention results in more accurate than previously available estimates of partial pressure blood gas pressures and does so while eliminating a significant risk for injury to the patient.

Methods and systems for diagnosing disorders, including, for example, disordered breathing, involve sensing one or more of a blood chemistry parameter and/or an expired gas parameter, such as expired respiratory gas concentration, blood gas concentration, and blood pH. Diagnosis of the disorder may be performed by a medical device, such as a respiratory therapy device or a cardiac therapy device, based on implantably detected blood gas/pH concentration/level or externally detected expired respiratory gas concentration. Cardiac and respiratory therapies for addressing the disorder may be adjusted based on the detected parameters.

A method for non-invasively determining pulmonary characteristics by measuring breath gas and blood gas and a display apparatus for the same, and for estimating major physiological characteristics, such as respiratory characteristics of lungs-pulmonary circulation system, cardiac functional characteristics, structural characteristics of lungs, etc. by applying primary measurement parameters obtained from ventilation gas and blood during breathing; and a display apparatus useful for the same.

A disposable, integrated extracorporeal blood circuit employed during cardiopulmonary bypass surgery performs gas exchange, heat transfer, and microemboli filtering functions in a way as to conserve volume, to reduce setup and change out times, to eliminate a venous blood reservoir, and to substantially reduce blood-air interface. Blood from the patient or prime solution is routed through an air removal device that is equipped with air sensors for detection of air. An active air removal controller removes detected air from blood in the air removal device. A disposable circuit support module is used to mount the components of the disposable, integrated extracorporeal blood circuit in close proximity and in a desirable spatial relationship to optimize priming and use of the disposable, integrated extracorporeal blood circuit. A reusable circuit holder supports the disposable circuit support module in relation to a prime solution source, the active air removal controller and other components.

A system and method for monitoring the arterial gas concentrations of a patient receiving percutaneous oxygenator support. The system comprises a percutaneous oxygenator for providing medical gases to the venous system of the patient via a catheter. Gases are also removed from the venous system via a catheter. The concentrations and flow rates of the gases provided and removed from the patient are monitored. A CPU analyzes the concentration and flow rate information to compute the arterial gas concentration of the patient.

A system for controlling an amount of at least one gas X in a subject's lung to target at least one end tidal partial pressure of at least one gas X (PetX^T) uses a control system for controlling the gas delivery device, wherein the control system implements a sequential gas delivery system and a feedback algorithm which compares a PetX^T for a respective breath of variable size and preferably a respective current PetX value measured by a measurement system, to obtain an error signal, the feedback algorithm adapted for generating a control signal based on the error signal, the control signal determining the amount of gas X to be inspired by the subject in at least a first portion of a respective ensuing respective inspiratory cycle to target PetX^T for the respective interval.

Methods and apparatus provide Cheyne-Stokes respiration (CSR) detection based on a blood gas measurements such as oximetry. In some embodiments, a duration, such as a mean duration of contiguous periods of changing saturation or re- saturation occurring in an epoch taken from a processed oximetry signal, is determined. An occurrence of CSR may be detected from a comparison of the duration and a threshold derived to differentiate saturation changes due to CSR respiration and saturation changes due to obstructive sleep apnea. The threshold may be a discriminant function derived as a classifier by an automated training method. The discriminant function may be further implemented to characterize the epoch for CSR based on a frequency analysis of the oximetry data. Distance from the discriminant function may be utilized to generate probability values for the CSR detection.

A gas therapy system involves sensing the blood gas concentration of the patient and adapting a gas therapy based on the sensed gas concentration. Disordered breathing may be detected bases on blood gas concentration, and gas or cardiac electrical therapy may be adapted to treat the detected disordered breathing. One or more of sensing the blood gas concentration, detecting disordered breathing, or adapting the therapy may be performed at least in part implantably. The gas therapy is delivered to the patient through an external respiratory device, such as a positive airway pressure device.

The present invention relates to a device (30) and a related method for determining a blood gas partial pressure in blood in a circulatory system of a subject (12) of interest. Also a system for ventilating a patient is disclosed. Temperature-related measurement values indicative of given blood temperature levels are detected. Oxygen saturation measurements of the blood of said subject (12) under consideration of said temperature-related measurement values are derived. A blood gas partial pressure of a monitored subject (12) from said derived oxygen saturation measurements is determined under consideration of present blood temperature levels of said subject (12). Preferably, pH-representative values attributable to present blood pH-values of the subject (12) are determined. More preferably, the pH-representative values are derived from an oxygen dissociation curve under consideration of changes in said derived oxygen saturation measurements of the blood attributable to detected temperature-related measurement values of the subject's blood.

A cartridge and system involving a joint spectroscopic and biosensor blood analyzer for measurement of at least two hemoglobin species in a patient's blood sample by spectroscopy, and measurement of at least pH of the blood sample by biosensor, for assessing the patient's oxygenation and acid-base status. The cartridge comprises a housing having a first housing member and a second housing member bonded together by a gasket. The housing comprises a cartridge inlet; a blood storage conduit; an optical chamber; a biosensor conduit; a waste receptacle; a vent; an air bladder, an air bladder exit port; and, an optical window and an aligned optical member, the aligned optical member being one of a reflecting member or a second optical window, and being positioned to align with at least a portion of the optical chamber and at least a portion of the optical window.

The invention provides a construction method for a rat hypoxia simulation model of a highland low pressure hypoxia simulation chamber. The method comprises the following steps: firstly, performing treadmill tests on experimental rats and screening out hypoxia-sensitive rats by simulating an environment with an altitude of 3500 meters in the highland low pressure hypoxia simulation chamber; secondly, selecting hypoxia-sensitive rats randomly and placing the selected rats in the highland low pressure hypoxia simulation chamber; thirdly establishing conditions for experimental rat hypoxia simulation of the highland low pressure hypoxia simulation chamber; fourthly, identifying the blood gas biochemical indexes and pathological indexes of the hypoxia-sensitive rats after hypoxia for 24-120h . The method is simple and easy to implement, is high in model making success rate, can truly reflect hypoxia injury conditions of animals and is high in stability.

The invention aims to provide an intelligent isolated organ long-term maintenance device and aims to solve the problem of long-term preservation of isolated organs. The intelligent isolated organ long-term maintenance device is characterized by comprising a perfusion module, a dialysis module, an oxygenation and blood gas regulation module, an automatic blood flow control module and a temperaturecontrol module, wherein the perfusion module is sequentially connected with the dialysis module, the oxygenation and blood gas regulation module, the automatic blood flow control module and the temperature control module to form a closed loop.

The invention belongs to the technical field of medical blood gas biochemical detection equipment, and relates to an integrated kit and a matched device thereof. The matched device consists of an integrated kit, an interface seat assembly, an analyzer bracket, a guide rail and a liquid path system; the integrated kit is composed of an encryption chip assembly, a kit body, a waste liquid bag assembly, a kit cover, a cleaning liquid bag assembly and a reagent bag assembly; and a cleaning liquid bag, a waste liquid bag and various standard liquid reagent bags are all internally packaged and sealed in the independent integrated kit in a combined and double-layer sealing mode. A double-needle layout is adopted on the waste liquid exhaust assembly, one needle is responsible for recovering wasteliquid, and the other needle is responsible for exhausting or overflowing the waste liquid; and once the waste liquid bag is filled with waste liquid or the waste liquid overflows along with gas, thewaste liquid can be reliably and completely recycled through the liquid path system, the safety of an operator is guaranteed to the maximum extent, and the integrated kit and the matched device can beapplied to medical diagnosis and clinical treatment of pneumonia infected by similar novel coronaviruses and used in cooperation with a blood gas biochemical analyzer.

The invention relates to a carbon dioxide biochemical analysis dry plate and a preparation method thereof, and belongs to the technical field of blood-gas biochemical sensors. The dry plate is used for detecting the concentration of carbon dioxide in a body fluid, and comprises a supporting layer, an insulating layer, a salt bridge, electrodes, a reference layer, a carbonate ion selective membrane and a buffering layer. According to the preparation method, metal/metal salt thin slice electrodes are prepared, the reference layer is attached onto the electrodes, the ratio of sodium chloride to potassium chloride in the reference layer and the water content of the reference layer are constant, the carbonate ion selective membrane and the buffering layer are sequentially attached onto the solid reference layer, carbon dioxide selective electrodes are prepared, and hydroxyl vinyl resin is utilized as a bonding agent for the carbonate ion selective membrane. The prepared dry plate provided by the invention overcomes the defects that the conventional ion selective electrode is complex to operate, high in use cost and maintenance cost, slow in response, not easy to carry, and the like, and has the advantages of being simple to operate, high in response speed, small in size, simple in preparation process, low in production cost, and suitable for industrialized production.

The invention relates to a drug for treating gastrectasia and a preparation method thereof. The drug is prepared from bighead atractylodes rhizome, pinellia ternate, endothelium corneum gigeriae galli, raw yam, rhizoma zingiberis, reddle, radices paeoniae alba, mangnolia officinalis and ginger by combination, can invigorate the spleen, supplement qi, eliminate dampness, induce diuresis, invigorate the spleen and the stomach, promote salivation, benefit lung, reinforce kidneys, arrest seminal emission, accelerate peristalsis hyperfunction, invigorate qi, benefit blood, regulate the blood qi, soothe liver of people, remove liver deficiency fire, relieve pain, diminish inflammation, promote the circulation of qi and remove qi stagnation, dry dampness, eliminate fullness, appetize and strengthen spleen, promote appetite and treat dyspepsia, has an exact curative effect of treating stomach duct pain, nausea, emesis, aphagosis and the like and has no side effects.

The invention relates to a heart rate and body temperature detection earphone and a system and method for monitoring human health. The earphone comprises a shell assembly, a main control PCB, a horn unit, a power supply module, a body temperature sensor and a heart rate and blood oxygen sensor, wherein the shell assembly comprises an ear rod shell and a shell cover which are connected with each other; the main control PCB is arranged in the ear rod shell; the horn unit, the power supply module, the body temperature sensor and the heart rate and blood oxygen sensor are all connected to the maincontrol PCB; the ear rod shell comprises a PCB shell part and a front sound cavity shell part which are communicated with each other; the front sound cavity shell part is placed in an ear of a person; a first opening is formed in the position, corresponding to the tragus incisura of the ear of the person, of the front sound cavity shell part; the body temperature sensor penetrates out of the first opening, makes close contact with the tragus incisura of the ear of the person and is exposed out of the shell assembly; the heart rate and blood oxygen sensor is in close contact with the tragus position of the human ear.

The invention relates to a dry plate for biochemical analysis of chloride ions and a preparation method thereof and belongs to the technical field of blood-gas biochemical sensors. The dry plate is used for detecting the chloride ion concentration of a body fluid and comprises a supporting layer, an insulating layer, a salt bridge, a silver/silver chloride electrode and a polymeric membrane. The silver/silver chloride electrode is prepared, the polymeric membrane is attached to an electrode silver chloride layer, chloride ion selection electrodes are prepared, the salt bridge is sealed in the insulating layer, the two chloride ion selection electrodes is in bonded with the supporting layer and the insulating layer to assemble the dry plate, and breakover between a fluid to be detected and a reference fluid is achieved through the salt bridge. Different from other ion selection electrodes, the dry plate uses the polymeric membrane to replace the reference fluid and an ion-selective membrane in a traditional chloride ion selection electrode, is simple in operation, high in response speed, small in size, convenient to carry, simple in preparation process, low in production cost and suitable for large-scale industrial production.

The invention discloses a blood gas analysis instrument which comprises a detection analysis main board for detecting and analyzing a blood sample and further comprises a bearing seat provided with a limiting sliding groove for enabling a test card to directionally slide, and a pressurizing assembly, a top heating limiting assembly, a bottom heating limiting assembly, a pushing assembly and a driving assembly arranged on the bearing seat. The pressurizing assembly and the top heating limiting assembly are located above the limiting sliding groove, and the bottom heating limiting assembly and the pushing assembly are located below the limiting sliding groove; the pressurizing assembly, the top heating limiting assembly, the pushing assembly and the bottom heating limiting assembly are sequentially arranged from top to bottom; the pressurizing assembly is used for extruding a gas storage area of the test card; the top heating limiting assembly is used for limiting and heating the top of the test card; and the bottom heating limiting assembly is used for limiting and heating the bottom of the test card. The blood gas analyzer is mainly used for detecting and analyzing a blood sample, and has the advantages of good detection effect and high accuracy.

The invention provides a multi-parameter detection array electrochemical sensor for continuous blood gas detection. The multi-parameter detection array electrochemical sensor sequentially comprises an electrode layer (7), an insulating layer (8), a hydrophilic film layer (9) and a shell protection layer (10) from a glass substrate (6) to the top, wherein the electrode layer (7) comprises three working electrodes and a common reference electrode (4), and the three working electrodes and the common reference electrode are integrated on the surface of the same glass substrate to realize array miniaturization. The sensor realizes synchronous and continuous detection of different substances in blood through cooperative work of a plurality of specific working electrodes.

The invention discloses a mixing device for a blood collector. The mixing device for the blood collector is used for mixing blood samples and anticoagulants and comprises a columnar mixing body with two ends open, a blood taking needle connection seat is arranged at one open end of the columnar mixing body while a blood taking tube connection seat is arranged at the other open end of the columnar mixing body, heparin anticoagulant pieces are arranged on the inner wall of the columnar mixing body, and a metal mixing ball is arranged in the columnar mixing body. The invention further discloses a self-filling arterial blood collector with the mixing device for the blood collector. The mixing device for the blood collector and the self-filling arterial blood collector have the advantages that anticoagulation effects in arterial blood collection and accuracy of blood gas analysis results can be improved, and blood samples can be taken out conveniently owing to automatic air feeding and discharging functions.

The invention provides a blood gas biochemical analyzer, and belongs to the technical field of medical instruments. The blood gas biochemical analyzer comprises a blood gas analyzer body and a test card, wherein the test card is matched with the blood gas biochemical analyzer body for use; the blood gas biochemical analyzer body comprises a shell, a test card base assembly, a signal acquisition assembly, a heat dissipation system assembly, a movement assembly and a main control board. A decorative cover and a main control board are arranged on the shell; the test card base assembly is installed in the shell, a base is arranged on the test card base assembly, and a test card hand feeling assembly and a card insertion in-place judgment assembly are arranged on the base; the signal acquisition assembly is mounted on the test card base assembly, a signal board PCBA is arranged on the signal acquisition assembly, and a probe is welded on the signal board PCBA. The operation assembly is mounted above the signal acquisition assembly; the heat dissipation system assembly is installed in the shell. According to the invention, the temperature is accurately controlled, and signal acquisition and related electric signals are fully protected and shielded, so that the test accuracy is higher.