36 results about "Cellular model" patented technology

An electronically stored model for a reservoir can include a plurality of hierarchical levels and a plurality of cells representing corresponding portions of the reservoir. The model can include a dimension and a cell number corresponding to the reservoir. A dimension of a cell of an nth hierarchical level can be defined in terms of a dimension of a cell of a first hierarchical level and an array of vertex coordinates along one or more axes can be generated. The model can include a ratio of dimensions among hierarchical levels for improved reservoir modeling. The model can include a ratio of permeability among hierarchical levels for improved reservoir modeling.

The invention discloses a scheduling method for an export container wharf pile-up space. Two-stage modeling is performed from plan allocation to dynamic allocation. At a pre-allocation stage, a block plan is researched, and the follow-up dynamic allocation is guided by the block plan. In the block plan, a block allocation model based on the ecological neutral theory is proposed. According to the block allocation model, container blocks are abstracted as islands, and container groups are abstracted as species, and thus, a process of allocating the container groups to the container blocks is escaped into a process that ecological selection is performed on the islands by a plurality of species. Based on the block allocation model, by aiming at the characteristic of the block plan problem, the block allocation model is optimized by the scheduling method for the export container wharf pile-up space, and an improved ecological neutral theory model is proposed. At a dynamic allocation stage, yard bay allocation and container space allocation are combined, solving is optimized by bi-objective combination, and a combination cellular automaton model is proposed. According to the combination cellular automaton model, the yard bay allocation is abstracted as an external cellular model, and the container space allocation is abstracted as an internal cellular model.

The invention relates to compounds having either agonist or antagonist activities for the neurotrophins NGF and BDNF and represented by monomeric or dimeric substituted dipeptides that are analogs of the exposed portions of loop 1 or loop 4 regions of these neurotrophins near or at a beta-turn of the respective loop. N-acylated substituents of these dipeptides are biostereoisomers of the amino acid residues preceding these dipeptide sequences in the neurotrophin primary structure. The dimeric structure is produced advantageously by using hexamethylenediamine to which dipeptides are attached via their carboxyl groups. The claimed compounds displayed neuroprotective and differentiation-inducing activities in cellular models and enhanced the amount of phosphorylated tyrosine kinase A and the heat shock proteins Hsp32 and Hsp70 in the concentration range of 10−9 to 10−5 M. They also displayed neuroprotective, anti-parkinsonian, anti-stroke, anti-ischemic, anti-depressant and anti-amnestic activities in animal models and were active in experimental models of Alzheimer's disease. These in vivo effects of the claimed compounds are displayed in the dose range of 0.01 to 10 mg / kg when administered intraperitoneally.