32 results about "Function blood" patented technology

A medical imaging system adaptively acquires anatomical images. The system includes a synchronization processor for providing a heart rate related synchronization signal derived from a patient cardiac function blood flow related parameter. The synchronization signal enables adaptive variation in timing of acquisition within successive heart cycles of each individual image frame of multiple sequential image frames. An image acquisition device initiates acquisition of anatomical images of a portion of patient anatomy in response to the synchronization signal. A display processor presents images, acquired by the acquisition device and synchronized with the synchronization signal, to a user on a reproduction device. The image acquisition device adaptively selects image pixel resolution of individual image frames of the multiple sequential image frames in response to data identifying a heart cycle segment so that successively acquired image frames have different image pixel resolution within a single heart cycle.

The present invention relates to the fields of Factor VII (FVII) and Factor VIIa (FVIIa) albumin linked polypeptides. More specifically, the invention relates to cDNA sequences coding for human Factor VII and Factor VIIa and derivatives genetically fused to a cDNA coding for human serum albumin which may be linked by oligonucleotides which code for intervening peptidic linkers such encoded derivatives exhibiting improved stability and extended functional plasma half-life, recombinant expression vectors containing such cDNA sequences, host cells transformed with such recombinant expression vectors, recombinant polypeptides and derivatives which do have biological activities of the unmodified wild type protein but having improved stability and prolonged shelf-life and processes for the manufacture of such recombinant proteins and their derivatives. The invention also covers a transfer vector for use in human gene therapy, which comprises such modified DNA sequences.

An ultrasound image acquisition device initiates acquisition of anatomical images of a portion of patient anatomy in response to a heart rate related synchronization signal. The ultrasound image acquisition device includes multiple ultrasound transducers for generating sound waves. The ultrasound transducers are arranged in different transducer groups oriented to enable acquisition of different ultrasound imaging information used in generating a single composite ultrasound image. A synchronization processor derives the heart rate related synchronization signal from a patient cardiac function blood flow related parameter. The synchronization signal enables adaptive activation of a particular group of the different transducer groups for acquisition of ultrasound imaging information used in generating the single composite ultrasound image. A display processor presents the single composite ultrasound image, acquired by the ultrasound image acquisition device, to a user on a reproduction device.

The invention relates to a tissue engineering vessel and a preparation method and an application thereof. The tissue engineering vessel uses a tubular gelatin / polycaprolactone electricity texture membrane as a support, and smooth muscle cells are evenly distributed in the support. The preparation method includes: a) spreading disinfected gelatin / polycaprolactone materials in a culture dish; b) collecting umbilical artery smooth muscle cells, evenly inoculating the umbilical artery smooth muscle cells on the surface of the gelatin / polycaprolactone electricity texture membrane to culture over the night, and forming a cell material composite electricity texture membrane; and c) twisting the cell material composite electricity texture membrane on a polyvinyl chloride (PVC) tube for culturing, and finally forming the tubular tissue engineering vessel. Cells of the tissue engineering vessel prepared by the method are evenly distributed, simultaneously the tissue engineering vessel has the advantages of being good in elasticity, moderate in hardness and compact in tissue structure, having smooth inner walls and abundant collagenous fibers, and being clear in self tissue boundary and the like. The characteristics of the tissue engineering vessel are close to that of living body vessels.

An ultrasound image acquisition device initiates acquisition of anatomical images of a portion of patient anatomy in response to a heart rate related synchronization signal. The ultrasound image acquisition device includes multiple ultrasound transducers for generating sound waves. The ultrasound transducers are arranged in different transducer groups oriented to enable acquisition of different ultrasound imaging information used in generating a single composite ultrasound image. A synchronization processor derives the heart rate related synchronization signal from a patient cardiac function blood flow related parameter. The synchronization signal enables adaptive activation of a particular group of the different transducer groups for acquisition of ultrasound imaging information used in generating the single composite ultrasound image. A display processor presents the single composite ultrasound image, acquired by the ultrasound image acquisition device, to a user on a reproduction device.

The invention provides a multifunctional thrombus treatment device and a using method thereof.The multifunctional thrombus treatment device comprises a guide wire, a variable-diameter thrombus extraction support, a fixing catheter and a recycling catheter, the density of a far-end net part of the variable-diameter thrombus extraction support is large, so that escaped small thrombus can be caught, and the thrombus can be recycled. A sliding opening is formed in the far end of the variable-diameter thrombus extraction support and sleeves the guide wire, the near end of the variable-diameter thrombus extraction support is connected with the far end of the fixed catheter, the diameter of the variable-diameter thrombus extraction support can be adjusted by adjusting the positions of the guide wire and the fixed catheter, and thrombus of different sizes in a blood vessel can be fully captured; the recycling catheter is arranged on the outer wall of the fixed catheter in a sleeving mode and can be used for containing the variable-diameter thrombus taking support, thrombus can be captured and netted to the maximum extent by repeatedly changing the diameter of the variable-diameter thrombus taking support, and large thrombus difficult to capture can be captured after being dissolved and reduced in advance through the fixed catheter and the recycling catheter. And various treatment methods such as thrombolysis, thrombus extraction and net thrombus can be completed at the same time.

The invention discloses a preparation method of a multifunctional intravascular stent. The preparation method comprises the following steps: firstly, preparing a dopamine coating on the surface of theintravascular stent through dopamine autopolymerization; then loading heparin into the chitosan functionalized graphene oxide, and further fixing the heparin-loaded graphene oxide on the surface of the intravascular stent with the dopamine coating to obtain the heparin-loaded intravascular stent; finally, immersing the intravascular stent in a rapamycin solution to fully adsorb and load rapamycin, and obtaining the multifunctional intravascular stent. Due to the antibacterial effect and the endothelial cell growth promoting effect of chitosan, the anticoagulation effect and the selective endothelial cell growth promoting effect of heparin and the anti-hyperplasia effect of rapamycin, the intravascular stent prepared through the method can inhibit clinical complications of stent implantation from multiple ways, and therefore the application effect of the intravascular stent is improved.

The invention relates to the technical field of blood purification and particularly relates to a multifunctional blood purification device. The multifunctional blood purification device comprises a blood purification device body, wherein a desk groove is formed in the outer wall of the blood purification device; a foldable desk is arranged in the cavity of the desk groove in a folded manner; a spacing ring is arranged on the side, far from the desk groove, of the blood purification device body; a hook rack is arranged in the cavity of the spacing ring; a hook table is arranged on the electrictelescopic rod output shaft of the hook rack; a plurality of hooks are arranged on the outer wall of the hook table in a rotating manner; a rotary column is arranged at the bottom of the blood purification device body in a rotating manner; the bottom of the rotary column is fixedly arranged at the top of a bottom plate; universal wheels are arranged at the bottom of the bottom plate; the output shaft of a first electric push rod arranged in the inner cavity of the bottom plate extends out of the bottom plate and is connected with a slide plate; a fixed cavity is formed in the bottom of the slide plate; a second electric push rod is arranged at the top of the inner cavity of the fixed cavity; the output shaft of the second electric push rod is provided with a piston; and the bottom of the fixed cavity is provided with a rubber pressure plate in a communicated manner. The multifunctional blood purification device has good stability, saves the space occupied by outward extension of hooks,and has strong practicality.

The invention discloses a multifunctional blood storage and transportation container, which is dual-use and peacetime-wartime blood storage and transportation equipment mainly used for blood transportation of blood stations at all levels. The informatization and network-based management can be implemented to the blood storage and transportation equipment. The multifunctional blood storage and transportation container is in a vehicle-mounted state, and is applicable to various transportation ways, such as water, land and air transportation when the emergency blood supply is needed. The equipment is of a three-container three-temperature internal structure which is divided into a -20 DEG C cooling chamber, 4 DEG C refrigerated blood storage chamber and a 22 DEG C blood storage chamber; the using temperature range has various choices as needed, the -20 DEG C cooling chamber and the 4 DEG C refrigerated blood storage chamber are internally provided with four light control channel type dual-way transmission equipments, damping systems and automatic binding devices, and the 22 DEG C blood storage chamber is internally provided with a dual oscillator. The top of the container is provided with an electronic control extensible simulated sunshade net, an electrical apparatus control system takes a microcomputer processor as a core master controller for full-automatic intelligent monitoring. The equipment is used for fully supporting the informatization and network-based management of blood, cold chains, equipments and flows.

The present invention provides a highly functional platelet production promoting agent which comprises one or a plurality of aryl hydrocarbon receptor (AhR) antagonists and one or a plurality of Rho-associated coiled-coil forming kinase (ROCK) inhibitors.

The invention discloses a multifunctional blood oxygen probe. The multifunctional blood oxygen probe comprises a probe body; the right side of the top of the probe body is electrically connected with an electric wire; a detector body is electrically connected to the top of the electric wire; the left side of the surface of the probe body is sleeved with a first frame sleeve, and the front side and the rear side of the right side of the first frame sleeve are both fixedly connected with insertion blocks; the right side of the surface of the probe body is sleeved with a second frame sleeve; the right sides of the insertion blocks penetrate into the second frame sleeve; clamping rods are arranged on the front side and the rear side of the second frame sleeve in a penetrating mode; the inner sides of the clamping rods penetrate into the insertion blocks; sliding blocks are slidably connected to the front side and the rear side of the second frame sleeve; and the outer sides of the sliding blocks are fixedly connected with a baffle. According to the multifunctional blood oxygen probe, the multifunctional effect can be achieved, and the problems that an existing blood oxygen probe is relatively single in function, inconvenience of different degrees can occur during detection, and the convenience of a user and the detection accuracy are affected are solved.

The invention belongs to the technical field of food processing, and discloses nutritional pig blood tofu and a preparation method thereof, and the preparation method comprises the following steps: uniformly dispersing cellulose ether in water, then uniformly mixing the cellulose ether with anticoagulant pig blood, adding a coagulant, standing for 5-15 minutes for solidification, and then freezing at-20 DEG C for 12-24 hours to obtain the pig blood tofu, wherein the anticoagulant pig blood is prepared by the following steps: uniformly dispersing an anticoagulant in fresh pig blood, filtering, and carrying out ultrasonic treatment on the filtrate for 2-3 minutes under the ultrasonic power of 200-500w, so as to obtain the anticoagulant pig blood. The pig blood tofu is prepared by adopting an ultrasonic technology and adding cellulose ether, so that erythrocyte walls in the pig blood tofu are broken, heme iron is released, the content of free heme iron which can be utilized by a human body is increased, and the multi-nutrition functional blood tofu which is high in iron utilization rate and has potential physiological functions of resisting oxidation, reducing blood sugar, reducing blood fat and the like is formed; the nutritional value of the pig blood bean curd is greatly improved.

The invention relates to a tissue engineering vessel and a preparation method and an application thereof. The tissue engineering vessel uses a tubular gelatin / polycaprolactone electricity texture membrane as a support, and smooth muscle cells are evenly distributed in the support. The preparation method includes: a) spreading disinfected gelatin / polycaprolactone materials in a culture dish; b) collecting umbilical artery smooth muscle cells, evenly inoculating the umbilical artery smooth muscle cells on the surface of the gelatin / polycaprolactone electricity texture membrane to culture over the night, and forming a cell material composite electricity texture membrane; and c) twisting the cell material composite electricity texture membrane on a polyvinyl chloride (PVC) tube for culturing, and finally forming the tubular tissue engineering vessel. Cells of the tissue engineering vessel prepared by the method are evenly distributed, simultaneously the tissue engineering vessel has the advantages of being good in elasticity, moderate in hardness and compact in tissue structure, having smooth inner walls and abundant collagenous fibers, and being clear in self tissue boundary and the like. The characteristics of the tissue engineering vessel are close to that of living body vessels.

The present invention relates to a bifunctional angiogenesis inhibitor having VEGF inhibitory activities and FGF inhibitory activities and capable of inhibiting VEGF and FGF dual factors or high sugar-induced cell proliferation, cell migration and / or lumen formation. The present invention also relates to use of the bifunctional vascular inhibitor for inhibiting retinal angiogenesis, such as diabetic retinopathy, age-related macular degeneration.

The present invention relates to nucleic acids and antibodies against SRPX2 and SRPX2 protein function in angiogenesis. Angiogenesis-related conditions, such as cancer or wound healing, can be treated by the composition comprising the SRPX2 antagonists or agonists, respectively.

The invention discloses a multifunctional anastomat for vascular surgery, and belongs to the field of medical auxiliary instruments, the multifunctional anastomat comprises an anastomosis fixing seat and a supporting ring, a fixing seat overturning groove is formed in the center of the upper end of the anastomosis fixing seat, and a supporting ring penetrating groove is formed in the center of the bottom of the fixing seat overturning groove; the bottom of the supporting ring penetrating groove is obliquely arranged towards the side face of the anastomosis fixing base in a penetrating mode, the first end of the supporting ring is fixedly connected to the side, opposite to the bottom of the supporting ring penetrating groove, of the anastomosis fixing base, the two sides of a blood vessel wound are fixed through a wound fixing base on the anastomosis fixing base, and then the inner wall of a blood vessel is supported through the supporting ring. By means of the installation mode of firstly fixing and then supporting, it is guaranteed that a blood vessel wound is fixed in a contraction state, fixing is firmer, the circulation area in the blood vessel is guaranteed, normal circulation of blood in the blood vessel at the wound position during healing is guaranteed, the device can adapt to the high-pressure working environment of the blood vessel, and the requirement for suture repair of the axial wound of the blood vessel wall is met.

The invention discloses a multifunctional blood group identification instrument, which is characterized by comprising a centrifugal chamber (1), a motor (2), a rotating shaft (3), a blood group card rotor assembly (4), a horizontal rotor assembly (5) and an angle rotor assembly (6); the rotating shaft (3) is arranged vertically, and the middle part of the rotating shaft (3) is rotatably connected to the bottom of the centrifugal chamber (1); the output end of the motor (2) is connected to the rotating shaft (3) The lower end is connected and used to drive the rotating shaft (3) to rotate; the upper end of the rotating shaft (3) is coaxially fixed with a spline shaft (3-1); the blood group card rotor assembly (4), the horizontal rotor assembly (5) ) and the angular rotor assembly (6) are located in the centrifugal chamber (1) and are sequentially mounted on the spline shaft (3-1) from bottom to top. The invention can realize multi-purpose of one machine, reduce equipment cost, and can select multiple functions at the same time or any one of them, and also avoid the problem that different rotors need to be disassembled and replaced during use.

The invention discloses a multifunctional autologous internal arteriovenous fistula limb fixing and protecting device for a hemodialysis patient, which comprises a limb fixing assembly including a base and an arm fixing part arranged on the base; a rotating clamping assembly comprising a clamping assembly and a rotating assembly, wherein the rotating assembly comprises a vertical rod, a movable joint, a transverse rod and a magnetic attraction piece arranged at the other end of the transverse rod; a clamping assembly clamped on a bed frame, wherein the vertical rod and the clamping assembly are integrally connected, and the transverse rod and the bottom end of the base are movably connected in a clamped mode through a magnetic attraction piece; and a control assembly comprising a control box, wherein a warm air assembly, an inflation assembly, a microprocessor, a control button and a power supply assembly are arranged in the control box; The device has the characteristics of fixing the arm of a patient, monitoring blood leakage, warming and keeping warm, lifting the position according to conditions and being integrally fixed and stable, the pain of the patient can be effectively reduced, and the use safety of internal fistula and the comfort of the patient are improved.

A test strip needle used for a multi-functional blood glucose meter. A test strip accommodating unit (201) configured to accommodate test strips (21) is disposed within the test strip needle used for a multi-functional blood glucose meter. The multiple test strips (21) are arranged along a direction of the test strip needle and in the test strip accommodating unit (201). Multiple test strips (21) are electrically connected. The test strip needle used for the multi-functional blood glucose meter also comprises a release device (202) for releasing the test strips (21). The present invention can be used multiple times while eliminating the need to manually change test strips in use, thus facilitating use by a user, reducing a time duration for blood to be exposed to the air, resulting in an increase in precision of a measuring result.

The invention discloses a multifunctional blood glucose measurement package. The measurement package includes a package body provided with a cavity inside; a cotton swab with double wiping heads, blood glucose test paper and a blood glucose needle are arranged in the cavity; the cotton swab includes a straight rod part, and a wiping head I and wiping heads II located on the two ends of the straight rod part; a cavity respectively communicating with the two wiping heads II is arranged in the straight rod part, and filed with alcohol; the connecting parts of the straight rod part and the wipingheads II are provided with creases for breaking; the end part of the package body is provided with a serrated easy-to-tear edge; and the outside of the package body is provided with a scanning two-dimensional code, and the package body is made of a transparent material. The measurement package is strong in functionality and can be widely applied to the field of auxiliary equipment for blood glucose measurement.

The invention provides a microfluidic detection chip, a kit and a whole blood multi-index detection method based on the same and an application of the microfluidic detection chip. The detection chip comprises two layers, the upper layer is a sample processing layer and the lower layer is a reaction layer, two or more fluid channels are arranged on the surface, facing the reaction layer, of the sample processing layer, and the two layers are closely overlapped to form a closed fluid channel system inside the chip. A plurality of biochemical indexes based on colorimetric measurement, such as liver function, kidney function, blood fat, electrolyte and the like are detected simultaneously in a small test card with a microfluidic chip technology. Difficulties in the application of the existingmicrofluidic technology are overcome, and the chip has low requirements for detection equipment, can be easily applied on site for POCT (point-of-care testing), and is applicable to large, medium andsmall medical institutions, emergency departments, community hospitals, family detection, scientific research and the like.

The invention discloses a FibroTouch-based non-alcoholic fatty liver disease rat model and manufacturing and detecting methods. The FibroTouch-based non-alcoholic fatty liver disease rat model comprises a plurality of mature rat individuals, and is characterized in that the selected rat individuals are bred in the same batch and have the same breeding condition, the body lengths and the body weights of the selected rat individuals are roughly the same, the selected rat individuals are healthy and free of diseases, the conversion coefficient of the body weight coefficient is 0.018, the body weight coefficient is equal to (Kg) / height (m) 2), the conversion coefficient is equal to (the body weight coefficient of the rat individuals / the body weight coefficient of the adult group), and the selected rat individuals are grouped according to male and female. According to theFibroTouch-based non-alcoholic fatty liver disease rat model and the manufacturing and detecting methods provided by the invention, the LSM and UAP values of an NAFLD patient are detected through Fibrotouch, and indexes such as liver function, blood fat and blood sugar, BMI and the like are combined, so that the liver fibrosis and lipolysis lesion degrees of the NAFLD patient are more accurately judged, the positive intervention of disease progression is facilitated, and the application value is obvious in clinic use.

A system and method for monitoring the blood pressure of a patient that allows for a device sensor to be recalibrated according to atmospheric pressure without removing the device sensor from inside the patient. This permits quickly monitoring the blood pressure of a patient if a re-zero is needed. The invention has a blood pressure monitor (BPM) that obtains an atmospheric pressure observation. The atmospheric pressure observation is adjusted and stored to memory as a zero value. The zero value is retrieved to recalibrate the system and method if a device sensor has been disconnected from and reconnected to the same or a different BPM, the patient has been moved such that the surroundings have been altered to make it necessary to recalibrate according to atmospheric pressure, and / or the device sensor has been connected to a different patient care monitor.

The invention discloses a multifunctional blood vessel cleaning robot. The robot comprises a control center, an imager, a manipulator, a recovery instrument, a protection device, an alarm device and the like. The control center is responsible for information receiving, information processing and instruction generation and sending. The imager determines the focus position, the shape and the blood vessel size and sends the information to the control center. A manipulator is the core technology of the invention and mainly comprises a manipulator, a mechanical arm and a power sensing device. A conical cutting knife is arranged in the mechanical arm, and thrombus cutting work is completed by receiving an instruction of the control center. The power sensing device is used for guaranteeing normalwork of thrombus cutting of the manipulator. The recovery instrument is responsible for recovering thrombus residues left in blood vessels after cutting. The protection device is installed outside the cutting knife, thrombus is directly cut off on the premise that the cutting knife does not make contact with blood vessels, and the alarm device is used for giving an alarm in time when the mechanical arm works abnormally to prevent the blood vessels from being damaged. The invention belongs to the minimally invasive technology, and has the advantages of short rehabilitation period and no need of adjuvant therapy.

The invention discloses a hemodialysis catheter with an extensible function. The hemodialysis catheter comprises a catheter body; the top of the catheter body communicates with a connecting seat; the top of the connecting seat communicates with an extension pipe A and an extension pipe B; the end, away from the connecting seat, of the extension pipe A communicates with a joint A; the end, away from the connecting seat, of the extension pipe B communicates with a joint B; a furcation assembly is arranged at the end, away from the connecting seat, of the catheter; the furcation assembly comprises a short furcation pipe and a long furcation pipe; a side hole is formed in the side wall of the short furcation pipe; a guide wire catheter C is connected to an inner cavity of the long furcation pipe; a bending and stretching component is movably inserted into an inner cavity of the guide wire catheter A; vertical long guide wires are movably inserted into inner cavities of a guide wire catheter B and guide wire catheter C correspondingly; and circulating holes are formed in bottom ends of the short furcation pipe and long furcation pipe correspondingly. After the hemodialysis catheter enters a heart from a blood vessel, the short furcation pipe can be bent and stretched, so that the short furcation pipe and the long furcation pipe can be separated, which guarantees a treatment effect of the hemodialysis catheter.