The invention discloses a
goose astrovirus egg-
yolk antibody compound and a preparation method thereof and relates to the field of veterinary biopreparations. To achieve the objective, the preparation method comprises the steps of 1) using a
goose astrovirus SD strain collected under CCTCC NO: V201815 as a vaccine producing viral strain to prepare an inactivation
antigen; 2) subjecting the inactivation
antigen to water phase preparation and
oil phase preparation, mixing a water phase and an
oil phase, and performing primary emulsification to obtain an immune
antigen; 3) inoculating the immune antigen to
layers so as to produce high-
immunity eggs; and 4) collecting
yolk from the high-
immunity eggs, disinfecting, separating
yolk, diluting the yolk, acidifying, extracting, preparing a stock
antibody solution, filtering, concentrating, and inactivating to obtain the
goose astrovirus refined egg-yolk
antibody.
Goose astrovirus can be prevented effectively, geese can be protected within the whole growth period, and farming benefit can be increased evidently.